X-ray structural analysis provides new insights into the mode of action of respiratory complex I
Proton-pumping respiratory complex I is among the largest and most complicated membrane protein complexes. Its function is critical for efficient energy supply in aerobic cells and malfunctions are implicated in many neurodegenerative disorders. Volker Zickermann in the group of Ulrich Brandt together with former CEF member Carola Hunte now published the X-ray crystallographic analysis of mitochondrial complex I in the journal Science.
Contact for further information: Ulrich Brandt, Molecular Bioenergetics, Cluster of Excellence Makromolecular Complexes, Niederrad Campus , Frankfurt am Main, Germany, Tel. +49 (0)69 6301-6925; brandt@zbc.kgu.de
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