CEF Top Publication List 2006-2013
(last update: Feb. 2013)
2013
Bono F, De Smet F, Herbert C, De Bock K, Georgiadou M, Fons P, Tjwa M, Alcouffe C, Ny A, Bianciotto M, Jonckx B, Murakami M, Lanahan A A, Michielsen C, Sibrac D, Dol-Gleizes F, Mazzone M, Zacchigna S, Herault J P, Fischer C, Rigon P, Ruiz de Almodovar C, Claes F, Blanc I, Poesen K, Zhang J, Segura I, Gueguen G, Bordes M F, Lambrechts D, Broussy R, van de Wouwer M, Michaux C, Shimada T, Jean I, Blacher S, Noel A, Motte P, Rom E, Rakic J M, Katsuma S, Schaeffer P, Yayon A, Van Schepdael A, Schwalbe H, Gervasio F L, Carmeliet G, Rozensky J, Dewerchin M, Simons M, Christopoulos A, Herbert J M, Carmeliet P (2013) Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties. Cancer Cell 23: 477–488
Crosetto N, Mitra A, Silva MJ, Bienko M, Dojer N, Wang Q, Karaca E, Chiarle R, Skrzypczak M, Ginalski K, Pasero P, Rowicka M, Dikic I (2013) Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing. Nature Methods 10:361–365
Herbert C, Schieborr U, Saxena K, Juraszek J, De Smet F, Alcouffe C, Bianciotto M, Saladino G, Sibrac D, Kudlinzki D, Sreeramulu S, Brown A, Rigon P, Herault J P, Lassalle G, Blundell T L, Rousseau F, Gils A, Schymkowitz J, Tompa P, Herbert J M, Carmeliet P, Gervasio F L, Schwalbe H, Bono F (2013) Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell 23: 489-501
2012
Althoff T, Davies KM, Schulze S, Joos F, Kühlbrandt W (2012) GRecon: a method for the lipid reconstitution of membrane proteins. Angew Chem Int Edit 51:8343-7
Belgnaoui SM, Paz S, Samuel S, Goulet ML, Sun Q, Kikkert M, Iwai K, Dikic I, Hiscott J, Lin R (2012) Linear Ubiquitination of NEMO Negatively Regulates the Interferon Antiviral Response through Disruption of the MAVS-TRAF3 Complex. Cell Host & Microbe 12:211-22
Brieke C, Rohrbach F, Gottschalk A, Mayer G, Heckel A (2012) Light-controlled tools. Angew Chem Int Edit 51:8446-76
Cajigas IJ, Tushev G, Will TJ, Dieck ST, Fuerst N, Schuman EM (2012) The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging. Neuron 74:453-466
Davies KM, Anselmi C, Wittig I, Faraldo-Gomez JD, Kühlbrandt W (2012) Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae. P Natl Acad Sci USA 109:13602-7
Eicher T, Cha HJ, Seeger MA, Brandstatter L, El-Delik J, Bohnert JA, Kern WV, Verrey F, Grutter MG, Diederichs K, Pos KM (2012) Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. P Natl Acad Sci USA 109:5687-92
Fischer F, Hamann A, Osiewacz HD (2012) Mitochondrial quality control: an integrated network of pathways. Trends Biochem Sci 37:284-292
Fromel T, Jungblut B, Hu J, Trouvain C, Barbosa-Sicard E, Popp R, Liebner S, Dimmeler S, Hammock BD, Fleming I (2012) Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols. P Natl Acad Sci USA 109:9995-10000
Fulda S, Rajalingam K, Dikic I (2012) Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications. EMBO Mol Med 4:545-556
Gao Y, Meyer B, Sokolova L, Zwicker K, Karas M, Brutschy B, Peng GH, Michel H (2012) Heme-copper terminal oxidase using both cytochrome c and ubiquinol as electron donors. P Natl Acad Sci USA 109:3275-3280
Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R (2012) Caged glutathione: triggering protein interaction by light. Angew Chem Int Edit 51:3960-3
Hakulinen J, Klyszejko AL, Hoffmann J, Eckhardt-Strelau L, Brutschy B, Vonck J, Meier T (2012) Structural study on the architecture of the bacterial ATP synthase Fo motor. P Natl Acad Sci USA 109:E2050-6
Heide H, Bleier L, Steger M, Ackermann J, Drose S, Schwamb B, Zornig M, Reichert AS, Koch I, Wittig I, Brandt U (2012) Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex. Cell Metab 16:538-549
Hergenreider E, Heydt S, Treguer K, Boettger T, Horrevoets AJG, Zeiher AM, Scheffer MP, Frangakis AS, Yin XK, Mayr M, Braun T, Urbich C, Boon RA, Dimmeler S (2012) Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol 14:249-256
Husson SJ, Steuer Costa W, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM, Lu H, Gottschalk A (2012) Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors. Curr Biol 22:1-10
Imre G, Heering J, Takeda AN, Husmann M, Thiede B, Heringdorf DMZ, Green DR, van der Goot FG, Sinha B, Dötsch V, Rajalingam K (2012) Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis. EMBO J 31:2615-2628
Kovacevic I, Hu J, Siehoff-Icking A, Opitz N, Griffin A, Perkins AC, Munn AL, Müller-Esterl W, Popp R, Fleming I, Jungblut B, Hoffmeister M, Oess S (2012) The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development. EMBO J 31:3309-3322
Lieblein AL, Buck J, Schlepckow K, Fürtig B, Schwalbe H (2012) Time-resolved NMR spectroscopic studies of DNA i-Motif folding reveal kinetic partitioning. Angew Chem Int Edit 51:250-253
Lieblein AL, Krämer M, Dreuw A, Fürtig B, Schwalbe H (2012) The nature of hydrogen bonds in Cytidine···H+···Cytidine DNA base pairs. Angew Chem Int Edit 51:4067-4070
Luce K, Osiewacz HD (2012) Increasing organismal healthspan by enhancing mitochondrial protein quality control. Nat Cell Biol 14:220
Nishino Y, Eltsov M, Joti Y, Ito K, Takata H, Takahashi Y, Hihara S, Frangakis AS, Imamoto N, Ishikawa T, Maeshima K (2012) Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. EMBO J 31:1644-53
Oberoi TK, Dogan T, Hocking JC, Scholz RP, Mooz J, Anderson CL, Karreman C, Heringdorf DMZ, Schmidt G, Ruonala M, Namikawa K, Harms GS, Carpy A, Macek B, Koster RW, Rajalingam K (2012) IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J 31:14-28
Pogoryelov D, Klyszejko AL, Krasnoselska GO, Heller EM, Leone V, Langer JD, Vonck J, Müller DJ, Faraldo-Gómez JD, Meier T (2012) Engineering rotor ring stoichiometries in the ATP synthase. P Natl Acad Sci USA 109:E1599-E1608
Rossier O, Octeau V, Sibarita JB, Leduc C, Tessier B, Nair D, Gatterdam V, Destaing O, Albiges-Rizo C, Tampé R, Cognet L, Choquet D, Lounis B, Giannone G (2012) Integrins β1 and β3 display distinct dynamic nanoscale organizations inside focal adhesions. Nat Cell Biol 14:1057 - 1067
Ruzzenente B, Metodiev MD, Wredenberg A, Bratic A, Park CB, Camara Y, Milenkovic D, Zickermann V, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Brandt U, Stewart JB, Gustafsson CM, Larsson NG (2012) LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs. EMBO J 31:443-456
Saibil HR, Seybert A, Habermann A, Winkler J, Eltsov M, Perkovic M, Castano-Diez D, Scheffer MP, Haselmann U, Chlanda P, Lindquist S, Tyedmers J, Frangakis AS (2012) Heritable yeast prions have a highly organized three-dimensional architecture with interfiber structures. P Natl Acad Sci USA 109:14906-14911
Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC (2012) Autophagic targeting of Src promotes cancer cell survival following reduced FAK signallin. Nat Cell Biol 14:51-U76
Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S (2012) RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans. P Natl Acad Sci USA 109:18944-18949
Schlegel K, Leone V, Faraldo-Gómez JD, Muller V (2012) Promiscuous archaeal ATP synthase concurrently coupled to Na(+) and H(+) translocation. P Natl Acad Sci USA 109:947-952
Symersky J, Pagadala V, Osowski D, Krah A, Meier T, Faraldo-Gomez JD, Mueller DM (2012) Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation. Nat Struct Mol Biol 19:485-U40
Tucci P, Agostini M, Grespi F, Markert EK, Terrinoni A, Vousden KH, Muller PAJ, Dötsch V, Kehrloesser S, Sayan BS, Giaccone G, Lowe SW, Takahashi N, Vandenabeele P, Knight RA, Levine AJ, Melino G (2012) Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. P Natl Acad Sci USA 109:15312-15317
van Wijk SJL, Fiskin E, Putyrski M, Pampaloni F, Hou J, Wild P, Kensche T, Grecco HE, Bastiaens P, Dikic I (2012) Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells. Molecular Cell:in press. doi 10.1016/j.molcel.2012.06.017
Wei RS, Gatterdam V, Wieneke R, Tampé R, Rant U (2012) Stochastic sensing of proteins with receptor-modified solid-state nanopores. Nat Nanotechnol 7:257-263
2011
Barthelme D, Dinkelaker S, Albers SV, Londei P, Ermler U, Tampé R (2011) Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1. P Natl Acad Sci USA 108:3228-3233
Davies KM, Strauss M, Daum B, Kief JH, Osiewacz HD, Rycovska A, Zickermann V, Kühlbrandt W (2011) Macromolecular organization of ATP synthase and complex I in whole mitochondria. P Natl Acad Sci USA 108:14121-14126
Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V (2011) DNA damage in oocytes induces a switch of the quality control factor TAp63± from dimer to tetramer. Cell 144:566-576
Dröse S, Krack S, Sokolova L, Zwicker K, Barth HD, Morgner N, Heide H, Steger M, Nubel E, Zickermann V, Kerscher S, Brutschy B, Radermacher M, Brandt U (2011) Functional dissection of the proton pumping modules of mitochondrial complex I. PLoS Biol 9:Article Number: e1001128
Grabbe C, Husnjak K, Dikic I (2011) The spatial and temporal organization of ubiquitin networks. Nat Rev Mol Cell Biol 12:295-307
Herget M, Baldauf C, Scholz C, Parcej D, Wiesmuller KH, Tampé R, Abele R, Bordignon E (2011) Conformation of peptides bound to the transporter associated with antigen processing (TAP). P Natl Acad Sci USA 108:1349-1354
Ikeda F, Deribe YL, Skanland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJL, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, Dikic I (2011) SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappa B activity and apoptosis. Nature 471:637-U120
Jonker HRA, Baumann S, Wolf A, Schoof S, Hiller F, Schulte KW, Kirschner KN, Schwalbe H, Arndt HD (2011) NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew Chem Int Edit 50:3308-3312
Kim SA, Tai CY, Mok LP, Mosser EA, Schuman EM (2011) Calcium-dependent dynamics of cadherin interactions at cell-cell junctions. P Natl Acad Sci USA 108:9857-9862
Kleinlogel S, Feldbauer K, Dempski RE, Fotis H, Wood PG, Bamann C, Bamberg E (2011) Ultra light-sensitive and fast neuronal activation with the Ca(2+)-permeable channelrhodopsin CatCh. Nat Neurosci 14:513-U152
Kleinlogel S, Terpitz U, Legrum B, Gokbuget D, Boyden ES, Bamann C, Wood PG, Bamberg E (2011) A gene-fusion strategy for stoichiometric and co-localized expression of light-gated membrane proteins. Nat Methods 8:1083-1088.
Krstić I, Hänsel R, Romainczyk O, Engels JW, Dötsch V, Prisner TF (2011) Long-range distance measurements on nucleic acids in cells by pulsed EPR spectroscopy. Angew Chem Int Edit 50:5070-5074
Kuipers JE, Coenen EA, Balgobind BV, Stary J, Baruchel A, de Haas V, de Bont E, Reinhardt D, Kaspers GJL, Cloos J, Danen-van Oorschot AA, den Boer ML, Marschalek R, Meyer C, Pieters R, Zwaan CM, van den Heuvel-Eibrink MM (2011) High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23). Blood 117:928-935
Kuster L, Grausenburger R, Fuka G, Kaindl U, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer LH, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grumayer R (2011) ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling. Blood 117:2658-2667
Lieblein AL, Buck J, Schlepckow K, Fürtig B, Schwalbe H (2011) Time-resolved NMR spectroscopic studies of DNA i-Motif folding reveal kinetic partitioning. Angew Chem Int Edit 51:250-253
Marinelli F, Kuhlmann SI, Grell E, Kunte HJ, Ziegler C, Faraldo-Gómez JD (2011) Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins. P Natl Acad Sci USA 108:E1285-E1292
McEwan DG, Dikic I (2011) The three musketeers of autophagy: phosphorylation, ubiquitylation and acetylation. Trends Cell Biol 21:195-201
Nozinovic S, Gupta P, Fürtig B, Richter C, Tullmann S, Duchardt-Ferner E, Holthausen MC, Schwalbe H (2011) Determination of the conformation of the 2 ' OH Group in RNA by NMR spectroscopy and DFT calculations. Angew Chem Int Edit 50:5397-5400
Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM (2011) Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell 144:67-78
Oschatz C, Maas C, Lecher B, Jansen T, Bjorkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin WA, Nilsson G, Renne T (2011) Mast cells Increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity 34:258-268
Rahighi S, Dikic I (2011) Conformational flexibility and rotation of the RING domain in activation of cullin-RING ligases. Nat Struct Mol Biol 18:863-865
Reimer D, Pos KM, Thines M, Grun P, Bode HB (2011) A natural prodrug activation mechanism in nonribosomal peptide synthesis. Nat Chem Biol 7:888-890
Rinnenthal J, Buck J, Ferner J, Wacker A, Fürtig B, Schwalbe H (2011) Mapping the landscape of RNA dynamics with NMR spectroscopy. Accounts Chem Res 44:1292-1301
Schleiff E, Becker T (2011) Common ground for protein translocation: access control for mitochondria and chloroplasts. Nat Rev Mol Cell Biol 12:48-59
Sentürk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A (2011) Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature 472:356-U123
Sommer MS, Daum B, Gross LE, Weis BLM, Mirus O, Abram L, Maier UG, Kühlbrandt W, Schleiff E (2011) Chloroplast Omp85 proteins change orientation during evolution. P Natl Acad Sci USA 108:13841-13846
Stefer S, Reitz S, Wang F, Wild K, Pang YY, Schwarz D, Bomke J, Hein C, Löhr F, Bernhard F, Denic V, Dötsch V, Sinning I (2011) Structural basis for tzil-anchored membrane protein biogenesis by the Get3-receptor complex. Science 333:758-762
Stirman JN, Crane MM, Husson SJ, Wabnig S, Schultheis C, Gottschalk A, Lu H (2011) Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans. Nat Methods 8:153-U78
Sziegat F, Wirmer-Bartoschek J, Schwalbe H (2011) Characteristics of human lysozyme and its disease-related mutants in their unfolded states. Angew Chem Int Edit 50:5514-5518
Ullrich SJ, Hellmich UA, Ullrich S, Glaubitz C (2011) Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR. Nat Chem Biol 7:263-270
van Wijk SJL, Muller S, Dikic I (2011) Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair. Genes Dev 25:1763-1769
Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT (2011) Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin. P Natl Acad Sci USA 108:17504-17509
von der Hocht I, van Wonderen JH, Hilbers F, Angerer H, MacMillan F, Michel H (2011) Interconversions of P and F intermediates of cytochrome c oxidase from Paracoccus denitrificans. P Natl Acad Sci USA 108:3964-3969
Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D, Dikic I (2011) Phosphorylation of the autophagy receptor optineurin restricts salmonella growth. Science 333:228-233
Yonehara K, Balint K, Noda M, Nagel G, Bamberg E, Roska B (2011) Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit. Nature 469:407-410
2010
Ackermann D, Schmidt TL, Hannam JS, Purohit CS, Heckel A, Famulok M (2010) A double-stranded DNA rotaxane. Nat Nanotechnol 5:436-442
Baldauf C, Schrodt S, Herget M, Koch J, Tampé R (2010) Single residue within the antigen translocation complex TAP controls the epitope repertoire by stabilizing a receptive conformation. P Natl Acad Sci USA 107:9135-9140
Bienko M, Green CM, Sabbioneda S, Crosetto N, Matic I, Hibbert RG, Begovic T, Niimi A, Mann M, Lehmann AR, Dikic I (2010) Regulation of translesion synthesis DNA polymerase h by monoubiquitination. Mol Cell 37:396-407
Bomar MG, D'Souza S, Bienko M, Dikic I, Walker GC, Zhou P (2010) Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases i and Rev1. Mol Cell 37:408-417
Bursen A, Schwabe K, Ruster B, Henschler R, Ruthardt M, Dingermann T, Marschalek R (2010) The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4. Blood 115:3570-3579
Buschmann S, Warkentin E, Xie H, Langer JD, Ermler U, Michel H (2010) The structure of cbb3 cytochrome oxidase provides insights into proton pumping. Science 329:327-329
Cherepanov AV, Glaubitz C, Schwalbe H (2010) High-resolution studies of uniformly 13C,15N-labeled RNA by solid-state NMR spectroscopy. Angew Chem Int Edit 49:4747-4750
Coutandin D, Ou HD, Lohr F, Dötsch V (2010) Tracing the protectors path from the germ line to the genome. P Natl Acad Sci USA 107:15318-15325
Deribe YL, Pawson T, Dikic I (2010) Post-translational modifications in signal integration. Nat Struct Mol Biol 17:666-672
Dieterich DC, Hodas JJL, Gouzer G, Shadrin IY, Ngo JT, Triller A, Tirrell DA, Schuman EM (2010) In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nat Neurosci 13:897-U149
Duchardt-Ferner E, Weigand JE, Ohlenschlager O, Schtnidtke SR, Suess B, Wöhnert J (2010) Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew Chem Int Edit 49:6216-6219
Gipson P, Mills DJ, Wouts R, Grininger M, Vonck J, Kühlbrandt W (2010) Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy. P Natl Acad Sci USA 107:9164-9
Grunwald C, Schulze K, Reichel A, Weiss VU, Blaas D, Piehler J, Wiesmüller KH, Tampé R (2010) In situ assembly of macromolecular complexes triggered by light. P Natl Acad Sci USA 107:6146-6151
Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestol K, Dikic I, Palmer R, Stenmark H (2010) Cindr interacts with anillin to control cytokinesis in drosophila melanogaster. Curr Biol 20:944-950
Hunte C, Zickermann V, Brandt U (2010) Functional modules and structural basis of conformational coupling in mitochondrial complex I. Science 329:448-451
Ikeda F, Crosetto N, Dikic I (2010) What determines the specificity and outcomes of ubiquitin signaling? Cell 143:677-681
Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EHK (2010) Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy. Nat Methods 7:637-U55
Lyubenova S, Maly T, Zwicker K, Brandt U, Ludwig B, Prisner TF (2010) Multifrequency pulsed electron paramagnetic resonance on metalloproteins. Accounts Chem Res 43:181-189
Maslennikov I, Klammt C, Hwang E, Kefala G, Okamura M, Esquivies L, Mors K, Glaubitz C, Kwiatkowski W, Jeon YH, Choe S (2010) Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. P Natl Acad Sci USA 107:10902-10907
Maslennikov I, Klammt C, Hwang E, Kefala G, Okamura M, Esquivies L, Mors K, Glaubitz C, Kwiatkowski W, Jeon YH, Choe S (2010) Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. P Natl Acad Sci USA 107:10902-10907
McEwan DG, Dikic I (2010) Not all autophagy membranes are created equal. Cell 141:564-566
O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ (2010) Visualization of macromolecular structures. Nat Methods 7:S42-55
Parcej D, Tampé R (2010) ABC proteins in antigen translocation and viral inhibition. Nat Chem Biol 6:572-580
Pogoryelov D, Krah A, Langer JD, Yildiz O, Faraldo-Gomez JD, Meier T (2010) Microscopic rotary mechanism of ion translocation in the F-0 complex of ATP synthases. Nat Chem Biol 6:891-899
Preiss L, Yildiz O, Hicks DB, Krulwich TA, Meier T (2010) A new type of proton coordination in an F1Fo-ATP synthase rotor ring. PLoS Biol 8:10
Ratje AH, Loerke J, Mikolajka A, Brunner M, Hildebrand PW, Starosta AL, Donhofer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu YN, Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn CMT (2010) Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature 468:713-U143
Rutishauser U, Ross IB, Mamelak AN, Schuman EM (2010) Human memory strength is predicted by theta-frequency phase-locking of single neurons. Nature 464:903-907
Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T, Acker-Palmer A (2010) Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465:487-491
Schulze S, Koster S, Geldmacher U, van Scheltinga ACT, Kühlbrandt W (2010) Structural basis of Na+-independent and cooperative substrate/product antiport in CaiT. Nature 467:233-U129
Schwalbe H, Rinnenthal J (2010) Thermodynamics: The world is flat. Nat Chem Biol 6:312-313
Silvers R, Buhr F, Schwalbe H (2010) The Molecular Mechanism of Spider-Silk Formation. Angew Chem Int Edit 49:5410-5412
Sobhanifar S, Schneider B, Löhr F, Gottstein D, Ikeya T, Mlynarczyk K, Pulawski W, Ghoshdastider U, Kolinski M, Filipek S, Güntert P, Bernhard F, Dötsch V (2010) Structural investigation of the C-terminal catalytic fragment of presenilin 1. P Natl Acad Sci USA 107:9644-9649
Tai HC, Schuman EM (2010) Angelman syndrome: Finding the lost arc. Cell 140:608-610
Taylor AM, Dieterich DC, Ito HT, Kim SA, Schuman EM (2010) Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron 66:57-68
Vivanco I, Rohle D, Versele M, Iwanami A, Kuga D, Oldrini B, Tanaka K, Dang J, Kubek S, Palaskas N, Hsueh T, Evans M, Mulholland D, Wolle D, Rajasekaran S, Rajasekaran A, Liau LM, Cloughesy TF, Dikic I, Brennan C, Wu H, Mischel PS, Perera T, Mellinghoff IK (2010) The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation. P Natl Acad Sci USA 107:6459-6464
Wild P, Dikic I (2010) Mitochondria get a Parkin' ticket. Nat Cell Biol 12:104-106
2009
Abele R, Tampé R (2009) Peptide trafficking and translocation across membranes in cellular signaling and self-defense strategies. Curr Opin Cell Biol 21:508-515
Armistead J, Khatkar S, Meyer B, Mark BL, Patel N, Coghlan G, Lamont RE, Liu SB, Wiechert J, Cattini PA, Koetter P, Wrogemann K, Greenberg CR, Entian KD, Zelinski T, Triggs-Raine B (2009) Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome. Am J Hum Genet 84:728-739
Bohnsack MT, Martin R, Granneman S, Ruprecht M, Schleiff E, Tollervey D (2009) Prp43 Bound at Different Sites on the Pre-rRNA Performs Distinct Functions in Ribosome Synthesis. Mol Cell 36:583-592
Brandes M, Willimann K, Bioley G, Levy N, Eberl M, Luo M, Tampé R, Levy F, Romero P, Moser B (2009) Cross-presenting human gamma delta T cells induce robust CD8(+) alpha beta T cell responses. P Natl Acad Sci USA 106:2307-2312
Bredenbeck J, Ghosh A, Nienhuys HK, Bonn M (2009) Interface-specific ultrafast two-dimensional vibrational spectroscopy. Accounts Chem Res 42:1332-42
Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Kowarz E, Schneider B, Raff T, Reinhardt R, Gokbuget N, Hoelzer D, Thiel E, Marschalek R (2009) The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group. Blood 113:4011-4015
Busche AEL, Aranko AS, Talebzadeh-Farooji M, Bernhard F, Dötsch V, Iwai H (2009) Segmental Isotopic Labeling of a Central Domain in a Multidomain Protein by Protein Trans-Splicing Using Only One Robust DnaE Intein. Angew Chem Int Edit 48:6128-6131
Camargo SMR, Singer D, Makrides V, Huggel K, Pos KM, Wagner CA, Kuba K, Danilczyk U, Skovby F, Kleta R, Penninger JM, Verrey F (2009) Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations. Gastroenterology 136:872-882
Dikic I, Wakatsuki S, Walters KJ (2009) Ubiquitin-binding domains - from structures to functions. Nat Rev Mol Cell Biol 10:659-671
Feldbauer K, Zimmermann D, Pintschovius V, Spitz J, Bamann C, Bamberg E (2009) Channelrhodopsin-2 is a leaky proton pump. P Natl Acad Sci USA 106:12317-12322
Gerum C, Silvers R, Wirmer-Bartoschek J, Schwalbe H (2009) Unfolded-State Structure and Dynamics Influence the Fibril Formation of Human Prion Protein13. Angew Chem Int Edit 48:9452-9456
Grabbe C, Dikic I (2009) Functional roles of Ubiquitin-like domain (ULD) and Ubiquitin-binding domain (UBD) containing proteins. Chem Rev 109:1481-1494
Höller D, Dikic I (2009) Targeting the ubiquitin system in cancer therapy. Nature 458:438-444
Janes PW, Wimmer-Kleikamp SH, Frangakis AS, Treble K, Griesshaber B, Sabet O, Grabenbauer M, Ting AY, Saftig P, Bastiaens PI, Lackmann M (2009) Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10. PLoS Biol 7:17
Kirkin V, Lamark T, Sou Y, Bjorkoy G, Nunn J, Bruun J, Shvets E, Mc Ewan D, Clausen T, Wild P, Bilusic I, Theurillat JP, Overvatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T (2009) A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates. Mol Cell 33:505-516
Krauter J, Wagner K, Schafer I, Marschalek R, Meyer C, Heil G, Schaich M, Ehninger G, Niederwieser D, Krahl R, Buchner T, Sauerland C, Schlegelberger B, Dohner K, Dohner H, Schlenk RF, Ganser A (2009) Prognostic factors in adult patients up to 60 years old with acute myeloid leukemia and translocations of chromosome band 11q23: Individual patient data-based meta-analysis of the German Acute Myeloid Leukemia Intergroup. J Clin Oncol 27:3000-3006
Kuhner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castano-Diez D, Chen WH, Devos D, Guell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Bottcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC (2009) Proteome Organization in a Genome-Reduced Bacterium. Science 326:1235-1240
Luce K, Osiewacz HD (2009) Increasing organismal healthspan by enhancing mitochondrial protein quality control. Nat Cell Biol 11:852-U168
Lyubenova S, Maly T, Zwicker K, Brandt U, Ludwig B, Prisner TF (2009) Multifrequency pulsed electron paramagnetic resonance on metalloproteins. Accounts Chem Res 43:181-189
Marcia M, Ermler U, Peng GH, Michel H (2009) The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. P Natl Acad Sci USA 106:9625-9630
Matsuki Y, Maly T, Ouari O, Karoui H, Le Moigne F, Rizzato E, Lyubenova S, Herzfeld J, Prisner TF, Tordo P, Griffin RG (2009) Dynamic Nuclear Polarization with a Rigid Biradical. Angew Chem Int Edit 48:4996-5000
Meurer S, Pioch S, Pabst T, Opitz N, Schmidt PM, Beckhaus T, Wagner K, Matt S, Gegenbauer K, Geschka S, Karas M, Stasch JP, Schmidt H, Müller-Esterl W (2009) Nitric Oxide-Independent Vasodilator Rescues Heme-Oxidized Soluble Guanylate Cyclase From Proteasomal Degradation. Circ Res 105:33-U91
Oancea G, O'Mara ML, Bennett WFD, Tieleman DP, Abele R, Tampé R (2009) Structural arrangement of the transmission interface in the antigen ABC transport complex TAP. P Natl Acad Sci USA 106:5551-5556
Pogoryelov D, Yildiz O, Faraldo-Gomez JD, Meier T (2009) High-resolution structure of the rotor ring of a proton-dependent ATP synthase. Nat Struct Mol Biol 16:1068-U88
Poulopoulos A, Aramuni G, Meyer G, Soykan T, Hoon M, Papadopoulos T, Zhang MY, Paarmann I, Fuchs C, Harvey K, Jedlicka P, Schwarzacher SW, Betz H, Harvey RJ, Brose N, Zhang WQ, Varoqueaux F (2009) Neuroligin 2 Drives Postsynaptic Assembly at Perisomatic Inhibitory Synapses through Gephyrin and Collybistin. Neuron 63:628-642
Rabl R, Soubannier V, Scholz R, Vogel F, Mendl N, Vasiljev-Neumeyer A, Korner C, Jagasia R, Keil T, Baumeister W, Cyrklaff M, Neupert W, Reichert AS (2009) Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. J Cell Biol 185:1047-1063
Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R, Kensche T, Uejima T, Bloor S, Komander D, Randow F, Wakatsuki S, Dikic I (2009) Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation p1098. Cell 136:1098-1109
Renner S, van Otterlo WAL, Dominguez Seoane M, Mocklinghoff S, Hofmann B, Wetzel S, Schuffenhauer A, Ertl P, Oprea TI, Steinhilber D, Brunsveld L, Rauh D, Waldmann H (2009) Bioactivity-guided mapping and navigation of chemical space. Nat Chem Biol 5:585-592
Rhein V, Song XM, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Drose S, Brandt U, Savaskan E, Czech C, Gotz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. P Natl Acad Sci USA 106:20057-20062
Sabbioneda S, Green CM, Bienko M, Kannouche P, Dikic I, Lehmann AR (2009) Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization P Natl Acad Sci USA, pp E20-E20 (Letter) vol 106)
Sapra KT, Damaghi M, Koster S, Yildiz O, Kühlbrandt W, Muller DJ (2009) One beta Hairpin after the Other: Exploring Mechanical Unfolding Pathways of the Transmembrane beta-Barrel Protein OmpG. Angew Chem Int Edit 48:8306-8308
Schiemann O, Cekan P, Margraf D, Prisner TF, Sigurdsson ST (2009) Relative Orientation of Rigid Nitroxides by PELDOR: Beyond Distance Measurements in Nucleic Acids. Angew Chem Int Edit 48:3292-3295
Schleiff E, Tampé R (2009) Membrane proteins take center stage in Frankfurt. Nat Chem Biol 5:135-139
Schmidt MHH, Bicker F, Nikolic I, Meister J, Babuke T, Picuric S, Müller-Esterl W, Plate KH, Dikic I (2009) Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal. Nat Cell Biol 11:873-U245
Sreeramulu S, Gande SL, Gobel M, Schwalbe H (2009) Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90-Cdc37, a Kinome Chaperone-Cochaperone, by Triterpene Celastrol. Angew Chem Int Edit 48:5853-5855
Timinszky G, Till S, Hassa PO, Hothorn M, Kustatscher G, Nijmeijer B, Colombelli J, Altmeyer M, Stelzer EHK, Scheffzek K, Hottiger MO, Ladurner AG (2009) A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol 16:923-U41
2008
Beli P, Mascheroni D, Xu DL, Innocenti M (2008) WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2. Nat Cell Biol 10:849-857
Bertaso F, Zhang C, Scheschonka A, de Bock F, Fontanaud P, Marin P, Huganir R, Betz H, Bockaert J, Fagni L, Lerner-Natoli M (2008) PICK1 uncoupling from mGluR7a causes absence-like seizures. Nat Neurosci 11:940-948
Bloor S, Ryzhakov G, Wagner S, Jonathan P, Butler G, Smith DL, Krumbach R, Dikic I, Randow F (2008) Signal processing by its coil zipper domain activates IKK gamma. P Natl Acad Sci USA 105:1279-1284
Burgdorf S, Scholz C, Kautz A, Tampé R, Kurts C (2008) Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation. Nat Immunol 9:558-566
Connell SR, Topf M, Qin Y, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CMT (2008) A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nat Struct Mol Biol 15:910-915
Denysenkov VP, Biglino D, Lubitz W, Prisner TF, Bennati M (2008) Structure of the tyrosyl biradical in mouse R2 ribonucleotide reductase from high-field PELDOR. Angew Chem Int Edit 47:1224-1227
Eltsov M, MacLellan KM, Maeshima K, Frangakis AS, Dubochet J (2008) Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ. P Natl Acad Sci USA 105:19732-19737
Essmann CL, Martinez E, Geiger JC, Zimmer M, Traut MH, Stein V, Klein R, Acker-Palmer A (2008) Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nat Neurosci 11:1035-1043
Grabbe C, Dikic I (2008) Cell biology boing blobal on ubiquitin. Science 322:872-873
Hamm P, Helbing J, Bredenbeck J (2008) Two-dimensional infrared spectroscopy of photoswitchable peptides. Annu Rev Phys Chem 59:291-317
Harms JM, Wilson DN, Schluenzen F, Connell SR, Stachelhaus T, Zaborowska Z, Spahn CMT, Fucini P (2008) Translational regulation via L11: Molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol Cell 30:26-38
Husnjak K, Elsasser S, Zhang NX, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D, Dikic I (2008) Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 453:481-488
Ihalainen JA, Paoli B, Muff S, Backus EHG, Bredenbeck J, Woolley GA, Caflisch A, Hamm P (2008) a-Helix folding in the presence of structural constraints. P Natl Acad Sci USA 105:9588-9593
Jaskolla TW, Lehmann W-D, Karas M (2008) 4-Chloro-α-cyanocinnamic acid is an advanced, rationally designed MALDI matrix. P Natl Acad Sci USA 105:12200-12205
Koglin A, Lohr F, Bernhard F, Rogov VV, Frueh DP, Strieter ER, Mofid MR, Guntert P, Wagner G, Walsh CT, Marahiel MA, Dötsch V (2008) Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature 454:907-911
Liewald JF, Brauner M, Stephens GJ, Bouhours M, Schultheis C, Zhen M, Gottschalk A (2008) Optogenetic analysis of synaptic function. Nat Methods 5:895 - 902
Lopez JJ, Shukla AK, Reinhart C, Schwalbe H, Michel H, Glaubitz C (2008) The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy. Angew Chem Int Edit 47:1668-1671
Madry C, Betz H, Geiger JRP, Laube B (2008) Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist. P Natl Acad Sci USA 105:12563-12568
Mahoney TR, Luo S, Round EK, Brauner M, Gottschalk A, Thomas JH, Nonet ML (2008) Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans. P Natl Acad Sci USA 105:16350-16355
Marafioti T, Paterson JC, Ballabio E, Reichard KK, Tedoldi S, Hollowood K, Dictor M, Hansmann ML, Pileri SA, Dyer MJ, Sozzani S, Dikic I, Shaw AS, Petrella T, Stein H, Isaacson PG, Facchetti F, Mason DY (2008) Novel markers of normal and neoplastic human plasmacytoid dendritic cells. Blood 111:3778-3792
Noren-Muller A, Wilk W, Saxena K, Schwalbe H, Kaiser M, Waldmann H (2008) Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis. Angew Chem Int Edit 47:5973-5977
Nosenko Y, Wiosna-Salyga G, Kunitski M, Petkova I, Singh A, Buma WJ, Thummel RP, Brutschy B, Waluk J (2008) Proton transfer with a twist? Femtosecond dynamics of 7-(2-pyridyl)-indole in condensed phase and in supersonic jets. Angew Chem Int Edit 47:6037-6040
Oreb M, Tews I, Schleiff E (2008) Policing Tic 'n' Toc, the doorway to chloroplasts. Trends Cell Biol 18:19-27
Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G (2008) Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov 7:738-745
Rasched G, Ackermann D, Schmidt TL, Broekmann P, Heckel A, Famulok M (2008) DNA minicircles with gaps for versatile functionalization. Angew Chem Int Edit 47:967-970
Reckel S, Sobhanifar S, Schneider B, Junge F, Schwarz D, Durst F, Lohr F, Guntert P, Bernhard F, Dötsch V (2008) Transmembrane segment enhanced labeling as a tool for the backbone assignment of alpha-helical membrane proteins. P Natl Acad Sci USA 105:8262-8267
Rubio M, Rinehart J, Krett B, Duvezin-Caubet AS, Reichert AS, Söll D, Alfonzo JD (2008) Mammalian mitochondira have the innate ability to import tRNAs by a mechanism distinct from protein import. P Natl Acad Sci USA 105:9186-9191
Schreiner P, Chen X, Husnjak K, Randles L, Zhang NX, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M (2008) Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature 453:548-552
Seeger MA, von Ballmoos C, Eicher T, Brandstatter L, Verrey F, Diederichs K, Pos KM (2008) Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB. Nat Struct Mol Biol 15:199-205
Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P (2008) The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. P Natl Acad Sci USA 105:13339-13344
Zagrovic B, Dikic I (2008) Childhood of a phoenix: modern biology in Eastern and South-Eastern Europe. Nat Rev Mol Cell Bio 9:333-336
2007
Al-Amoudi A, Diez DC, Betts MJ, Frangakis AS (2007) The molecular architecture of cadherins in native epidermal desmosomes. Nature 450:832-U8
Bredenbeck J, Helbing J, Nienhaus K, Nienhaus GU, Hamm P (2007) Protein ligand migration mapped by nonequilibrium 2D-IR exchange spectroscopy. P Natl Acad Sci USA 104:14243-14248
Buck J, Furtig B, Noeske J, Wohnert J, Schwalbe H (2007) Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution. P Natl Acad Sci USA 104:15699-15704
Connell SR, Takemoto C, Wilson DN, Wang HF, Murayama K, Terada T, Shirouzu M, Rost M, Schuler M, Giesebrecht J, Dabrowski M, Mielke T, Fucini P, Yokoyama S, Spahn CMT (2007) Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Mol Cell 25:751-764
Datta PP, Wilson DN, Kawazoe M, Swami NK, Kaminishi T, Sharma MR, Booth TM, Takemoto C, Fucini P, Yokoyama S, Agrawal RK (2007) Structural aspects of RbfA action during small ribosomal subunit. Mol Cell 28:434-445
Diller A, Roy E, Gast P, van Gorkom HJ, de Groot HJM, Glaubitz C, Jeschke G, Matysik J, Alia A (2007) N-15 photochemically induced dynamic nuclear polarization magic-angle spinning NMR analysis of the electron donor of photosystem II. P Natl Acad Sci USA 104:12767-12771
Faraldo-Gomez JD, Roux B (2007) On the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases. P Natl Acad Sci USA 104:13643-13648
Höller D, Hecker CM, Wagner S, Rogov V, Dötsch V, Dikic I (2007) E3-independent monoubiquitination of ubiquitin-binding proteins. Mol Cell 26:891-898
Hsu STD, Fucini P, Cabrita LD, Launay H, Dobson CM, Christodoulou J (2007) Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy. P Natl Acad Sci USA 104:16516-16521
Ihalainen JA, Bredenbeck J, Pfister R, Helbing J, Chi L, van Stokkum IHM, Woolley GA, Hamm P (2007) Folding and unfolding of a photoswitchable peptide from picoseconds to microseconds. P Natl Acad Sci USA 104:5383-5388
Kirkin V, Dikic I (2007) Role of ubiquitin- and Ubl-binding proteins in cell signaling. Curr Opin Cell Biol 19:199-205
Ludden MJW, Mulder A, Tampé R, Reinhoudt DN, Huskens J (2007) Molecular printboards as a general platform for protein immobilization: A supramolecular solution to nonspecific adsorption. Angew Chem Int Edit 46:4104-4107
Mookerjee RP, Wiesenthal A, Icking A, Hodges SJ, Davies NA, Schilling K, Sen S, Williams R, Novelli M, Müller-Esterl W, Jalan R (2007) Increased gene and protein expression of the novel eNOS regulatory protein NOSTRIN and a variant in alcoholic hepatitis. Gastroenterology 132:2533-2541
Radmark O, Werz O, Steinhilber D, Samuelsson B (2007) 5-Lipoxygenase: regulation of expression and enzyme activity. Trends Biochem Sci 32:332-341
Reese ML, Dakoji S, Bredt DS, Dötsch V (2007) The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a. Nat Struct Mol Biol 14:155-163
Sargin B, Choudhary C, Crosetto N, Schmidt MHH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwable J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, Muller-Tidow C, Dikic I, Serve H (2007) Flt3-dependent transformation by inactivating c-Cbl mutations in AML. Blood 110:1004-1012
Scheckhuber CQ, Erjavec N, Tinazli A, Hamann A, Nystrom T, Osiewacz HD (2007) Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models. Nat Cell Biol 9:99-U129
Scheschonka A, Tang ZS, Betz H (2007) Sumoylation in neurons: nuclear and synaptic roles? Trends Neurosci 30:85-91
Schiemann O, Prisner TF (2007) Long-range distance determinations in biomacromolecules by EPR spectroscopy. Q Rev Biophys 40:1-53
Schmidt TL, Nandi CK, Rasched G, Parui PP, Brutschy B, Famulok M, Heckel A (2007) Polyamide struts for DNA architectures. Angew Chem Int Edit 46:4382-4384
Schwalbe H, Buck J, Furtig B, Noeske J, Wohnert J (2007) Structures of RNA switches: Insight into molecular recognition and tertiary structure. Angew Chem Int Edit 46:1212-1219
Segura I, Essmann CL, Weinges S, Acker-Palmer A (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat Neurosci 10:301-310
Sharma MR, Wilson DN, Datta PP, Barat C, Schluenzen F, Fucini P, Agrawal RK (2007) Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins. P Natl Acad Sci USA 104:19315-19320
Tinazli A, Piehler J, Beuttler M, Guckenberger R, Tampé R (2007) Native protein nanolithography that can write, read and erase. Nat Nanotechnol 2:220-225
Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, Watzke N, Wood PG, Bamberg E, Nagel G, Gottschalk A, Deisseroth K (2007) Multimodal fast optical interrogation of neural circuitry. Nature 446:633-639
2006
Bond PJ, Faraldo-Gomez JD, Deol SS, Sansom MSP (2006) Membrane protein dynamics and detergent interactions within a crystal: A simulation study of OmpA. P Natl Acad Sci USA 103:9518-9523
Brandt U (2006) Energy converting NADH : Quinone oxidoreductase (Complex I) Annu Rev Biochem, pp 69-92 vol 75)
Carrozzo R, Wittig I, Santorelli FM, Bertini E, Hofmann S, Brandt U, Schägger H (2006) Subcomplexes of human ATP synthase mark mitochondrial biosynthesis disorders. Ann Neurol 59:265-275
Denysenkov VP, Prisner TF, Stubbe J, Bennati M (2006) High-field pulsed electron-electron double resonance spectroscopy to determine the orientation of the tyrosyl radicals in ribonucleotide reductase. P Natl Acad Sci USA 103:13386-13390
Heckel A, Buff MCR, Raddatz MSL, Muller J, Potzsch B, Mayer G (2006) An anticoagulant with light-triggered antidote activity. Angew Chem Int Edit 45:6748-6750
Hirzel K, Muller U, Latal AT, Huelsmann S, Grudzinska J, Seeliger MW, Betz H, Laube B (2006) Hyperekplexia phenotype of glycine receptor alpha 1 subunit mutant mice identifies Zn2+ as an essential endogenous modulator of glycinergic neurotransmission. Neuron 52:679-690
Höller D, Crosetto N, Blagoev B, Raiborg C, Tikkanen R, Wagner S, Kowanetz K, Breitling R, Mann M, Stenmark H, Dikic I (2006a) Regulation of ubiquitin-binding proteins by monoubiquitination. Nat Cell Biol 8:163-U45
Höller D, Hecker CM, Dikic I (2006b) Ubiquitin and ubiquitin-like proteins in cancer pathogenesis. Nat Rev Cancer 6:776-788
Husnjak K, Dikic I (2006) EGFR trafficking: parkin' in a jam. Nat Cell Biol 8:787-788
Ikeda F, Dikic I (2006) CYLD in Ubiquitin Signaling and Tumor Pathogenesis. Cell 125:643-645
Koglin A, Mofid MR, Lohr F, Schafer B, Rogov VV, Blum MM, Mittag T, Marahiel MA, Bernhard F, Dötsch V (2006) Conformational switches modulate protein interactions in peptide antibiotic synthetases. Science 312:273-276
Kusebauch U, Cadamuro SA, Musiol HJ, Lenz MO, Wachtveitl J, Moroder L, Renner C (2006) Photocontrolled folding and unfolding of a collagen triple helix. Angew Chem Int Edit 45:7015-7018
Noren-Muller A, Reis-Correa I, Prinz H, Rosenbaum C, Saxena K, Schwalbe H, Vestweber D, Cagna G, Schunk S, Schwarz O, Schiewe H, Waldmann H (2006) Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. P Natl Acad Sci USA 103:10606-10611
Olkhova E, Hunte C, Screpanti E, Padan E, Michel H (2006) Multiconformation continuum electrostatics analysis of the NhaA Na+/H+ antiporter of Escherichia coli with functional implications. P Natl Acad Sci USA 103:2629-2634
Rakonjac M, Fischer L, Provost P, Werz O, Steinhilber D, Samuelsson B, Radmark O (2006) Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A(4) production. P Natl Acad Sci USA 103:13150-13155
Schluenzen F, Takemoto C, Wilson DN, Kaminishi T, Harms JM, Hanawa-Suetsugu K, Szaflarski W, Kawazoe M, Shirouzu M, Nierhaus KH, Yokoyama S, Fucini P (2006) The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation (vol 13, pg 871, 2006). Nat Struct Mol Biol 13:1033-1033
Schulze K, Mulder A, Tinazli A, Tampé R (2006) Controlling the activity of the 20S proteasome complex by synthetic gatekeepers. Angew Chem Int Edit 45:5702-5705
Seeger MA, Schiefner A, Eicher T, Verrey F, Diederichs K, Pos KM (2006) Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism. Science 313:1295-1298
Seet BT, Dikic I, Zhou MM, Pawson T (2006) Reading protein modifications with interaction domains. Nat Rev Mol Cell Bio 7:473-483
Stasch JP, Schmidt PM, Nedvetsky PI, Nedvetskaya TY, Kumar A, Meurer S, Deile M, Taye A, Knorr A, Lapp H, Muller H, Turgay Y, Rothkegel C, Tersteegen A, Kemp-Harper B, Müller-Esterl W, Schmidt H (2006) Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels. J Clin Invest 116:2552-2561
Vogtherr M, Saxena K, Hoelder S, Grimme S, Betz M, Schieborr U, Pescatore B, Robin M, Delarbre L, Langer T, Wendt KU, Schwalbe H (2006) NMR characterization of kinase p38 dynamics in free and ligand-bound forms. Angew Chem Int Edit 45:993-997
