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The Cluster of Excellence Frankfurt (CEF) "Macromolecular Complexes" was a centre for the investigation of macromolecular complexes based in Frankfurt am Main from November 2006 until October 2019. CEF was selected in the 2006 excellence initiative for substantial funding by the Deutsche Forschungsgemeinschaft (DFG) for an initial 5 year period. In 2012 the DFG funding was extended for another 5 years.  In CEF, scientists of Goethe University Frankfurt and two Max Planck Institutes investigated the structure and function of large macromolecular complexes, in particular membrane proteins and their assemblies, complexes involved in signal transduction and quality control, and RNA-protein complexes. The Cluster was dedicated to scientific excellence and early independence of young researchers.


Examples of CEF publications in the journal Nature:

Faelber et al. published 10 July 2019 online by Nature
Hofmann, Januliene, Mehdipour et al. published 17 July 2019 online by Nature
Bhogaraju et al. published 22 July 2019 online by Nature

For further top publications of CEF members click here






Goethe University from the air
Goethe University image video



CEF was funded by the




Contact: T. Schuler, Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany, tanja.schuler@bmls.de