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CEF Top Publication List 2007-2017

 

2017

Bhaskara RM, Linker SM, Vögele M, Köfinger J, Hummer G (2017) Carbon nanotubes mediate fusion of lipid vesicles. ACS Nano 11: 1273–1280. http://dx.doi.org/10.1021/acsnano.6b05434

Bischoff FC, Werner A, John D, Boeckel JN, Melissari MT, Grote P, Glaser SF, Demolli S, Uchida S, Michalik KM, Meder B, Katus HA, Haas J, Chen W, Pullamsetti SS, Seeger W, Zeiher AM, Dimmeler S*, Zehendner CM* (2017) Identification and functional characterization of hypoxia-induced endoplasmic reticulum stress regulating lncRNA (HypERlnc)in pericytes. Circ Res: published online 15 June 2017. http://dx.doi.org/10.1161/circresaha.116.310531

Cai X, Shi Y, Pöhlmann N, Revermann O, Bahner I, Pidot S, Wesche F, Lackner H, Büchel C, Kaiser M, Richter C, Schwalbe H, Stinear T, Zeeck A, Bode H (2017) Structure and biosynthesis of isatropolones, bioactive amine-scavenging fluorescent natural products from Streptomyces Gö66. Angew Chem Int Ed 56: 4945-4949. http://dx.doi.org/10.1002/anie.201701223

Chang B-J, Perez Meza VD, Stelzer EHK (2017) csiLSFM combines light-sheet fluorescence microscopy and coherent structured illumination for a lateral resolution below 100 nm. P Natl Acad Sci USA: published online 24 April 2017. http://dx.doi.org/10.1073/pnas.1609278114

Chiavazzo E, Covino R, Coifman RR, Gear CW, Georgiou AS, Hummer G, Kevrekidis IG (2017) Intrinsic map dynamics exploration for uncharted effective free-energy landscapes. P Natl Acad Sci USA: published online 20 June 2017. http://dx.doi.org/10.1073/pnas.1621481114

Diamanti MA, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski AK, Richter B, Beli P, Hu Y, Saleh M, Mittelbronn M, Dikic I, Greten FR (2017) IKKα controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med, 214: 423-437. http://dx.doi.org/10.1084/jem.20161867

Fiskin E, Bhogaraju S, Herhaus L, Kalayil S, Hahn M, Dikic I (2017) Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA. Nat Commun 8: 14004. http://dx.doi.org/10.1038/ncomms14004

Gajewski J, Buelens F, Serdjukow S, Janszen M, Cortina N, Grubmüller H*, Grininger M* (2017) Engineering fatty acid synthases for directed polyketide production. Nat Chem Biol 13: 363–365. http://dx.doi.org/10.1038/nchembio.2314

Gajewski J, Pavlovic R, Fischer M, Boles E*, Grininger M* (2017) Engineering fungal de novo fatty acid synthesis for short chain fatty acid production. Nat Commun 8: 14650. http://dx.doi.org/10.1038/ncomms14650

Haberman N, Huppertz I, Attig J, König J, Wang Z, Hauer C, Hentze MW, Kulozik AE, Le Hir H, Curk T, Sibley CR, Zarnack K, Ule J (2017) Insights into the design and interpretation of iCLIP experiments. Genome Biol 18: 7. http://dx.doi.org/10.1186/s13059-016-1130-x

Halbleib K, Pesek K, Covino R, Hofbauer HF, Wunnicke D, Hänelt I, Hummer G, Ernst R (2017) Activation of the unfolded protein response by lipid bilayer stress. Mol Cell: published online 6 July 2017. http://dx.doi.org/10.1016/j.molcel.2017.06.012

Helmling C, Wacker A, Wolfinger MT, Hofacker IL, Hengesbach M, Fuertig B, Schwalbe H (2017) NMR structural profiling of transcriptional intermediates reveals riboswitch regulation by metastable RNA conformations. J Am Chem Soc, published online 30 January 2017. http://dx.doi.org/10.1021/jacs.6b10429

Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A, Kotter P, Berninghausen O, Becker T, Beckmann R*, Tampe R* (2017) Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation. Nat Struct Mol Biol, published online 3 April 2017. http://dx.doi.org/10.1038/nsmb.3396

Kim YB, Wacker A, Laer KV, Rogov VV, Suess B, Schwalbe H (2017) Ligand binding to 2'-deoxyguanosine sensing riboswitch in metabolic context. Nucleic Acids Res 45: 5375-5386. http://dx.doi.org/10.1093/nar/gkx016

Leisegang MS, Fork C, Josipovic I, Richter F, Preussner J, Hu J, Miller MJ, Epah JN, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ, Brandes RP (2017) Long noncoding RNA MANTIS facilitates endothelial angiogenic function. Circulation: published online 28 March 2017 http://dx.doi.org/10.1161/circulationaha.116.026991

Lucas T, Schäfer F, Müller P, Emig S, Heckel A, Dimmeler S (2017) Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice. Nat Commun: 183814. http://dx.doi.org/10.1038/ncomms15162

Mühleip AW, Dewar CE, Schnaufer A, Kühlbrandt W*, Davies KM* (2017) In situ structure of trypanosomal ATP synthase dimer reveals a unique arrangement of catalytic subunits. P Natl Acad Sci USA 114: 992–997. http://dx.doi.org/10.1073/pnas.1612386114

Manavski Y, Abel T, Hu J, Kleinlützum D, Buchholz CJ, Belz C, Augustin HG, Boon RA, Dimmeler S (2017) Endothelial transcription factor KLF2 negatively regulates liver regeneration via induction of activin A. P Nat Acad Sci USA: published online 27 March 2017. http://dx.doi.org/10.1073/pnas.1613392114

Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, Tomasiak TM, Brüchert S, Joseph B, Abele R, Oliéric V, Wang M, Diederichs K, Hummer G, Stroud RM, Pos KM, Tampé R (2017) Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP. P Natl Acad Sci USA, published online 9 January 2017, http://dx.doi.org/10.1073/pnas.1620009114

Peng H, Yang J, Li G, You Q, Han W, Li T, Gao D, Xie X, Lee B-H, Du J, Hou J, Zhang T, Rao H, Huang Y, Li Q, Zeng R, Hui L, Wang H, Xia Q, Zhang X, He Y, Komatsu M, Dikic I, Finley D, Hu R (2017) Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell Res: published online 21 March 2017. http://dx.doi.org/10.1038/cr.2017.40

Pescher M, van Wilderen L, Gruetzner S, Slavov C, Wachtveitl J, Hecht S, Bredenbeck J (2017) Ultrafast light-driven substrate expulsion from the active site of a photoswitchable catalyst. Angew Chem Int Ed: published online 2 June 2017. http://dx.doi.org/10.1002/anie.201702861

Sambandan S, Akbalik G, Kochen L, Rinne J, Kahlstatt J, Glock C, Tushev G, Alvarez-Castelao B, Heckel A*, Schuman EM* (2017) Activity-dependent spatially localized miRNA maturation in neuronal dendrites. Science 355: 634-637. http://dx.doi.org/10.1126/science.aaf8995

Scherr J, Parey K, Klusch N, Murphy BJ, Balser S, Neuhaus A, Zickermann V, Kühlbrandt W, Terfort A, Rhinow D (2017) Self-perforated hydrogel nanomembranes facilitate structural analysis of proteins by electron cryo-microscopy. ACS Nano: http://dx.doi.org/10.1021/acsnano.7b03099

Seyfried P, Eiden L, Grebenovsky N, Mayer G, Heckel A (2017) Photo-tethers for the (multi-)cyclic, conformational caging of long oligonucleotides. Angew Chem Int Edit 56: 359–363. http://dx.doi.org/10.1002/anie.201610025

Stolz A, Putyrski M, Kutle I, Huber J, Wang C, Major V, Sidhu SS, Youle RJ, Rogov VV, Dötsch V, Ernst A, Dikic I (2017) Fluorescence‐based ATG8 sensors monitor localization and function of LC3/GABARAP proteins. EMBO J 36: 549-564, http://dx.doi.org/10.15252/embj.201695063

Strobl F, Schmitz A, Stelzer EHK (2017) Improving your four-dimensional image: traveling through a decade of light-sheet-based fluorescence microscopy research. Nat Protoc 12: 1103-1109. http://dx.doi.org/10.1038/nprot.2017.028

van Wijk SJL, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, Grumati P, Kaulich M, Sou Y-s, Komatsu M, Greten FR, Fulda S, Heilemann M*, Dikic I* (2017) Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation. Nat Microbiol 2: 17066. http://dx.doi.org/10.1038/nmicrobiol.2017.66

Warhaut S, Mertinkus KR, Höllthaler P, Fürtig B, Heilemann M, Hengesbach M, Schwalbe H (2017) Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy. Nucleic Acids Res 45: 5512-5522. http://dx.doi.org/10.1093/nar/gkx110

Wilkes M, Madej MG, Kreuter L, Rhinow D, Heinz V, De Sanctis S, Ruppel S, Richter RM, Joos F, Grieben M, Pike ACW, Huiskonen JT, Carpenter EP, Kühlbrandt W, Witzgall R, Ziegler C (2017) Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2. Nat Struct Mol Biol 24: 123–130. http://dx.doi.org/10.1038/nsmb.3357

Wirmer-Bartoschek J, Bendel LE, Jonker HRA, Grün JT, Papi F, Bazzicalupi C, Messori L, Gratteri P, Schwalbe H (2017) Solution NMR structure of a ligand/hybrid-2-G-quadruplex complex reveals rearrangements that affect ligand binding. Angew Chem Int Edit: published online 19 May 2017. http://dx.doi.org/10.1002/anie.201702135

Zhu Z, Zhou YJ, Krivoruchko A, Grininger M, Zhao ZK, Nielsen J (2017) Expanding the product portfolio of fungal type I fatty acid synthases. Nat Chem Biol 13: 360–362. http://dx.doi.org/10.1038/nchembio.2301

 

2016

Bhogaraju S, Kalayil S, Liu Y, Bonn F, Colby T, Matic I, Dikic I (2016) Phosphoribosylation of ubiquitin promotes serine ubiquitination and impairs conventional ubiquitination. Cell 167: 1636-1649.e13. http://dx.doi.org/10.1016/j.cell.2016.11.019

Buhr F, Jha S, Thommen M, Mittelstaet J, Kutz F, Schwalbe H, Rodnina Marina V, Komar Anton A (2016) Synonymous codons direct cotranslational folding toward different protein conformations. Mol Cell 61:341-351 http://dx.doi.org/10.1016/j.molcel.2016.01.008

Covino R, Ballweg S, Stordeur C, Michaelis JB, Puth K, Wernig F, Bahrami A, Ernst AM, Hummer G, Ernst R (2016) A eukaryotic sensor for membrane lipid saturation. Mol Cell 63:1-11 http://dx.doi.org/10.1016/j.molcel.2016.05.015

Daury L, Orange F, Taveau JC, Verchere A, Monlezun L, Gounou C, Marreddy RKR, Picard M, Broutin I, Pos KM, Lambert O (2016) Tripartite assembly of RND multidrug efflux pumps. Nat Commun 7:10731-10731 http://dx.doi.org/10.1038/ncomms10731

Diekmann R, Wolfson DL, Spahn C, Heilemann M, Schüttpelz M, Huser T (2016) Nanoscopy of bacterial cells immobilized by holographic optical tweezers. Nat Commun 7: 13711. http://dx.doi.org/10.1038/ncomms13711

Elkins JM, Fedele V, Szklarz M, Azeez KRA, Salah E, Mikolajczyk J, Romanov S, Sepetov N, Huang XP, Roth BL, Zen AA, Fourches D, Muratov E, Tropsha A, Morris J, Teicher BA, Kunkel M, Polley E, Lackey KE, Atkinson FL, Overington JP, Bamborough P, Müller S, Price DJ, Willson TM, Drewry DH, Knapp S, Zuercher WJ (2016) Comprehensive characterization of the published kinase inhibitor set. Nat Biotechnol 34:95-103 http://dx.doi.org/10.1038/nbt.3374

Fichte MAH, Weyel XMM, Junek S, Schäfer F, Herbivo C, Goeldner M, Specht A, Wachtveitl J, Heckel A (2016) Three-dimensional control of DNA hybridization by orthogonal two-color two-photon uncaging. Angew Chem-Int Edit 55: 8948-8952. http://dx.doi.org/10.1002/anie.201603281

Fiskin E, Bionda T, Dikic I, Behrends C (2016) Global analysis of host and bacterial ubiquitinome in response to Salmonella Typhimurium infection. Mol Cell 62: 967-81. http://dx.doi.org/10.1016/j.molcel.2016.04.015

Gomes LC, Odedra D, Dikic I, Pohl C (2016) Autophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation in C. elegans. Autophagy 12:DOI: 10.1080/15548627.2015.1136771 http://dx.doi.org/10.1080/15548627.2015.1136771

Hahn A, Parey K, Bublitz M, Mills Deryck J, Zickermann V, Vonck J, Kühlbrandt W, Meier T (2016) Structure of a complete ATP synthase dimer reveals the molecular basis of inner mitochondrial membrane morphology. Mol Cell 63:445-456 http:/dx.doi.org/10.1016/j.molcel.2016.05.037

Kaur H, Lakatos-Karoly A, Vogel R, Nöll A, Tampé R, Glaubitz C (2016) Coupled ATPase-adenylate kinase activity in ABC transporters. Nat Commun 7: 13864. http://dx.doi.org/10.1038/ncomms13864

Kiosze-Becker K, Ori A, Gerovac M, Heuer A, Nürenberg-Goloub E, Rashid UJ, Becker T, Beckmann R, Beck M, Tampé R (2016) Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry. Nat Commun 7: 13248. http://dx.doi.org/10.1038/ncomms13248

Lehnert E, Mao J, Mehdipour AR, Hummer G, Abele R, Glaubitz C, Tampé R (2016) Antigenic peptide recognition on the human ABC transporter TAP resolved by DNP-enhanced solid-state NMR spectroscopy. J Am Chem SocEpub ahead of print 23 September 2016 http://dx.doi.org/10.1021/jacs.6b07426

Kollmannsperger A, Sharei A, Raulf A, Heilemann M, Langer R, Jensen KF, Wieneke R, Tampé R (2016) Live-cell protein labelling with nanometre precision by cell squeezing. Nat Commun 7:article number 10372 http://dx.doi.org/10.1038/ncomms10372

Kühlbrandt W, Davies KM (2016) Rotary ATPases: a new twist to an ancient machine. Trends Biochem Sci 41:106-116 dx.doi.org/10.1016/j.tibs.2015.10.006

Lamb CA, Nuhlen S, Judith D, Frith D, Snijders AP, Behrends C, Tooze SA (2016) TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic. EMBO J 35:281-301 http://dx.doi.org/10.15252/embj.201592695

Martínez-Limón A, Alriquet M, Lang W-H, Calloni G, Wittig I, Vabulas RM (2016) Recognition of enzymes lacking bound cofactor by protein quality control. P Natl Acad Sci USA, Epub ahead of print 12 October 2016 http://dx.doi.org/10.1073/pnas.1611994113

Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, El Oualid F, Kawasaki M, Freund SMV, Ovaa H, Komander D (2016) Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature 538: 402-405. http://dx.doi.org/10.1038/nature19836

Mühleip AW, Joos F, Wigge C, Frangakis AS, Kühlbrandt W, Davies KM (2016) Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria. P Natl Acad Sci USA 113:8442-8447 http://dx.doi.org/10.1073/pnas.1525430113

Müller-McNicoll M, Botti V, Domingues AMD, Brandl H, Schwich OD, Steiner MC, Curk T, Poser I, Zarnack K, Neugebauer KM (2016) SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export. Genes Dev 30:553-566 http://dx.doi.org/10.1101/gad.276477.115

Murn J, Teplova M, Zarnack K, Shi Y, Patel DJ (2016) Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt. Nat Struct Mol Biol 23:16-23 http://dx.doi.org/10.1038/nsmb.3140

Neyer S, Kunz M, Geiss C, Hantsche M, Hodirnau V-V, Seybert A, Engel C, Scheffer MP, Cramer P, Frangakis AS (2016) Structure of RNA polymerase I transcribing ribosomal DNA genes. Nature advance online publication 14 November 2016: http://dx.doi.org/10.1038/nature20561

Steinwand S, Yu Z, Hecht S, Wachtveitl J (2016) Ultrafast dynamics of photoisomerization and subsequent unfolding of an oligoazobenzene foldamer. J Am Chem Soc, http://dx.doi.org/10.1021/jacs.6b07720

Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Lunella FF, Jae N, Rossbach O, Amrhein C, Sigala F, Boon RA, Furtig B, Manavski Y, You X, Uchida S, Keller T, Boeckel JN, Franco-Cereceda A, Maegdefessel L, Chen W, Schwalbe H, Bindereif A, Eriksson P, Hedin U, Zeiher AM, Dimmeler S (2016) Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation. Nat Med, published online 5 September 2016, http://dx.doi.org/10.1038/nm.4172

Syed YA, Zhao C, Mahad D, Mobius W, Altmann F, Foss F, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN (2016) Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta Neuropathol. 131:281-298 http://dx.doi.org/10.1007/s00401-015-1521-1

Thevarpadam J, Bessi I, Binas O, Gonçalves DPN, Slavov C, Jonker HRA, Richter C, Wachtveitl J, Schwalbe H, Heckel A (2016) Photoresponsive formation of an intermolecular minimal G-quadruplex motif. Angew Chem-Int Edit 55:2738-2742 http://dx.doi.org/10.1002/anie.201510269

Venkataramani V, Herrmannsdorfer F, Heilemann M, Kuner T (2016) SuReSim: simulating localization microscopy experiments from ground truth models. Nat Methods 13: 319-321. http://dx.doi.org/10.1038/Nmeth.3775

von Wangenheim D, Fangerau J, Schmitz A, Smith RS, Leitte H, Stelzer EHK, Maizel A (2016) Rules and self-organizing properties of post-embryonic plant organ cell division patterns. Curr Biol 26:439-449 http://dx.doi.org/10.1016/j.cub.2015.12.047

von Delbrück M, Kniss A, Rogov VV, Pluska L, Bagola K, Löhr F, Güntert P, Sommer T, Dötsch V (2016) The CUE domain of Cue1 aligns growing ubiquitin chains with Ubc7 for rapid elongation. Mol Cell 62: http://dx.doi.org/10.1016/j.molcel.2016.04.031

 

2015

Allegretti M, Klusch N, Mills DJ, Vonck J, Kühlbrandt W, Davies KM (2015) Horizontal membrane-intrinsic a-helices in the stator a-subunit of an F-type ATP synthase. Nature 521:237-240

Bechara C, Nöll A, Morgner N, Degiacomi MT, Tampé R, Robinson CV (2015) A subset of annular lipids is linked to the flippase activity of an ABC transporter. Nat Chem 7:255-262 

Bohnert M, Zerbes RM, Davies KM, Muhleip AW, Rampelt H, Horvath SE, Boenke T, Kram A, Perschil I, Veenhuis M, Kühlbrandt W, van der Klei IJ, Pfanner N, van der Laan M (2015) Central role of Mic10 in the mitochondrial contact site and cristae organizing system. Cell Metab 21:747-755

Buhr F, Kohl-Landgraf J, tom Dieck S, Hanus C, Chatterjee D, Hegelein A, Schuman EM, Wachtveitl J, Schwalbe H (2015) Design of photocaged puromycin for nascent polypeptide release and spatiotemporal monitoring of translation. Angew Chem Int Ed 54:3717-3721

Chiocchetti AG, Kopp M, Waltes R, Haslinger D, Duketis E, Jarczok TA, Poustka F, Voran A, Graab U, Meyer J, Klauck SM, Fulda S, Freitag CM (2015) Variants of the CNTNAP2 5 ' promoter as risk factors for autism spectrum disorders: a genetic and functional approach. Mol Psychiatr 20:839-849

Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I (2015) Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes. Circ Res 117:157-165

Eltsov M, Dubé N, Yu Z, Pasakarnis L, Haselmann-Weiss U, Brunner D, Frangakis AS (2015) Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography. Nat Cell Biol 17:605-614

Finan K, Raulf A, Heilemann M (2015) A set of homo-oligomeric standards allows accurate protein counting. Angew Chem Int Ed Engl, Epub ahead of print, 20 August 2015, doi: 10.1002/anie.201505664

Fischbach H, Döring M, Nikles D, Lehnert E, Baldauf C, Kalinke U, Tampé R (2015) Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets. Nat Commun 6:DOI: 10.1038/ncomms7199

Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, Marroquin N, Nordin F, Hübers A, Weydt P, Pinto S, Press R, Millecamps S, Molko N, Bernard E, Desnuelle C, Soriani M-H, Dorst J, Graf E, Nordström U, Feiler MS, Putz S, Boeckers TM, Meyer T, Winkler AS, Winkelman J, Carvalho Md, Thal DR, Otto M, Brännström T, Volk AE, Kursula P, Danzer KM, Lichtner P, Dikic I, Meitinger T, Ludolph AC, Strom TM, Andersen PM, Weishaupt JH (2015) Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci 18:631–636 

Gao S, Nagpal J, Schneider M, Kozjak-Pavlovic V, Nagel G, Gottschalk A (2015) Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp. Nat Commun 6:article 8046

Genau HM, Huber J, Baschieri F, Akutsu M, Dötsch V, Farhan H, Rogov V, Behrends C (2015) CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling. Mol Cell 57:995-1010

Joseph B, Sikora A, Bordignon E, Jeschke G, Cafiso DS, Prisner TF (2015) Distance measurement on an endogenous membrane transporter in E. coli cells and native membranes using EPR spectroscopy. Angew Chem-Int Edit 54:6196-6199

Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, Mauthe M, Katona I, Qualmann B, Weis J, Reggiori F, Kurth I, Hübner CA, Dikic I (2015) Regulation of endoplasmic reticulum turnover by selective autophagy. Nature, published online 3 June 2015, doi:10.1038/nature14498

Kim JM, Wu SP, Tomasiak TM, Mergel C, Winter MB, Stiller SB, Robles-Colmanares Y, Stroud RM, Tampé R, Craik CS, Cheng YF (2015) Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter. Nature 517:396-U598

Kmita K, Wirth C, Warnau J, Guerrero-Castillo S, Hunte C, Hummer G, Kaila VRI, Zwicker K, Brandt U, Zickermann V (2015) Accessory NUMM (NDUFS6) subunit harbors a Zn-binding site and is essential for biogenesis of mitochondrial complex I. P Natl Acad Sci USA 112:5685-5690

Leone V, Pogoryelov D, Meier T, Faraldo-Gomez JD (2015) On the principle of ion selectivity in Na+/H+-coupled membrane proteins: Experimental and theoretical studies of an ATP synthase rotor. Proc Natl Acad Sci USA 112:E1057-E1066

McEwan DG, Popovic D, Gubas A, Terawaki S, Suzuki H, Stadel D, Coxon FP, Stegmann DMd, Bhogaraju S, Maddi K, Kirchof A, Gatti E, Helfrich MH, Wakatsuki S, Behrends C, Pierre P, Dikic I (2015) PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Mol Cell 57:39–54

McEwan DG, Richter B, Claudi B, Wigge C, Wild P, Farhan H, McGourty K, Coxon FP, Franz-Wachtel M, Perdu B, Akutsu M, Habermann A, Kirchof A, Helfrich MH, Odgren PR, Hul WV, Frangakis AS, Rajalingam K, Macek B, Holden DW, Bumann D, Dikic I (2015) PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection. Cell Host Microbe 17:58–71

Pfreundschuh M, Alsteens D, Wieneke R, Zhang C, Coughlin SR, Tampé R, Kobilka BK, Müller DJ (2015) Identifying and quantifying two ligand-binding sites while imaging native human membrane receptors by AFM. Nat Commun 6:DOI: 10.1038/ncomms9857 

Salvucci O, Ohnuki H, Maric D, Hou X, Li XR, Yoon SO, Segarra M, Eberhart CG, Acker-Palmer A, Tosato G (2015) EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun 6:DOI: 10.1038/ncomms7576

Sanchez CG, Su Q, Schonherr H, Grininger M, Noll G (2015) Multi-ligand-Bbnding flavoprotein dodecin as a key element for reversible surface modification in nano-biotechnology. ACS Nano 9:3491-3500

Stadel D, Millarte V, Tillmann Kerstin D, Huber J, Tamin-Yecheskel B-C, Akutsu M, Demishtein A, Ben-Zeev B, Anikster Y, Perez F, Dötsch V, Elazar Z, Rogov V, Farhan H, Behrends C (2015) TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export. Mol Cell 60:89-104

Stamatelopoulos K, Sibbing D, Rallidis LS, Georgiopoulos G, Stakos D, Braun S, Gatsiou A, Sopova K, Kotakos C, Varounis C, Tellis CC, Kastritis E, Alevizaki M, Tselepis AD, Alexopoulos P, Laske C, Keller T, Kastrati A, Dimmeler S, Zeiher AM, Stellos K (2015) Amyloid-Beta (1-40) and the risk of death from cardiovascular causes in patients with coronary heart disease. J Am Coll Cardiol 65:904-916

Stelzer EHK (2015) Light-sheet fluorescence microscopy for quantitative biology. Nat. Methods 12:23-26

Strale P, Duchesne L, Peyret G, Montel L, Nguyen T, Png E, Tampé R, Troyanovsky S, Hénon S, Ladoux B, Mège R (2015) The formation of ordered nanoclusters controls cadherin anchoring to actin and cell-cell contact fluidity. J Cell Biol 210:333-346

tom Dieck S, Kochen L, Hanus C, Heumüller M, Bartnik I, Nassim-Assir B, Merk K, Mosler T, Garg S, Bunse S, Tirrel DA, Schuman EM (2015) Direct visualization of newly synthesized target proteins in situ. Nat Methods 12:411-414 

Wieneke R, Raulf A, Kollmannsperger A, Heilemann M, Tampé R (2015) SLAP: Small labeling pair for single-molecule super-resolution imaging. Angew Chem Int Edit 127:10354–10357

You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM (2015) Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity. Nat Neurosci 18:603-610 

Yuet KP, Doma MK, Ngo JT, Sweredoski MJ, Graham RLJ, Moradian A, Hess S, Schuman EM, Sternberg PW, Tirrell DA (2015) Cell-specific proteomic analysis in Caenorhabditis elegans. Proc Natl Acad Sci USA 112:2705-2710

Zickermann V, Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C, Brandt U (2015) Mechanistic insight from the crystal structure of mitochondrial complex I. Science 347:44-49

Zollmann T, Moiset G, Tumulka F, Tampé R, Poolman B, Abele R (2015) Single liposome analysis of peptide translocation by the ABC transporter TAPL. Proc Natl Acad Sci USA 112:2046-2051

 

2014

Akbalik G, Schuman EM (2014) mRNA, live and unmasked. Science 343:375-376

Angerer H, Radermacher M, Malkowska M, Steger M, Zwicker K, Heide H, Wittig I, Brandt U, Zickermann V (2014) The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity. Proc Nati Acad of Sci USA 111:5207-5212

AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald J (2014) Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nat Commun 5, article 5810

Assmus B, Leistner DM, Schachinger V, Erbs S, Elsasser A, Haberbosch W, Hambrecht R, Sedding D, Yu JT, Corti R, Mathey DG, Barth C, Mayer-Wehrstein C, Burck I, Sueselbeck T, Dill T, Hamm CW, Tonn T, Dimmeler S, Zeiher AM, Grp R-AS (2014) Long-term clinical outcome after intracoronary application of bone marrow-derived mononuclear cells for acute myocardial infarction: migratory capacity of administered cells determines event-free survival. Eur Heart J 35:1275-1283

Belz K, Schoeneberger H, Wehner S, Weigert A, Bonig H, Klingebiel T, Fichtner I, Fulda S (2014) Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly. Blood 124:240-250

Chen YK, Zhang ZF, Tang XQ, Li JP, Glaubitz C, Yang J (2014) Conformation and topology of diacylglycerol kinase in E. coli membranes revealed by solid-state NMR spectroscopy. Angew Chem Int Edit 53:5624-5628

Daum B, Quax TEF, Sachse M, Mills DJ, Reimann J, Yildiz O, Hader S, Saveanu C, Forterre P, Albers SV, Kühlbrandt W, Prangishvili D (2014) Self-assembly of the general membrane-remodeling protein PVAP into sevenfold virus-associated pyramids. Proc Natl Acad Sci USA 111:3829-3834

Dieck ST, Hanus C, Schuman EM (2014) SnapShot: local protein translation in dendrites. Neuron 81:958

Garvalov BK, Foss F, Henze A-T, Bethani I, Gräf-Höchst S, Singh D, Filatova A, Dopeso H, Seidel S, Damm M, Acker-Palmer A, Acker T (2014) PHD3 regulates ​EGFR internalization and signalling in tumours. Nat Commun 5, article 5577

Gatterdam V, Ramadass R, Stoess T, Fichte MAH, Wachtveitl J, Heckel A, Tampé R (2014) Three-dimensional protein networks assembled by two-photon activation. Angew Chem Int Edit 53:5680-5684

Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC, Acker-Palmer A (2014) The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development. Dev Cell 28:381-393

Gold V, Ieva R, Walter A, Pfanner N, van der Laan M, Kühlbrandt W (2014) Visualizing active membrane protein complexes by electron cryo-tomography. Nat Commun 5
, article 4129

Gomes LC, Dikic I (2014) Autophagy in antimicrobial immunity. Mol Cell 54:224-233

Grossmann N, Vakkasoglu AS, Hulpke S, Abele R, Gaudet R, Tampé R (2014) Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Nat Commun 5, article 5419

Grumati P, Dikic I (2014) Germline polymorphisms in RNF31 regulate linear ubiquitination and oncogenic signaling. Cancer Discov 4:394-396

Hengesbach M, Schwalbe H (2014) Structural basis for regulation of ribosomal RNA 2'-o-methylation. Angew Chem Int Ed 53:1742-1744

Henze A-T, Garvalov BK, Seidel S, Cuesta AM, Ritter M, Filatova A, Foss F, Dopeso H, Essmann CL, Maxwell PH, Reifenberger G, Carmeliet P, Acker-Palmer A, Acker T (2014) Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nat Commun 5, article 5582

Hernandez VH, Gehrt A, Reuter K, Jing Z, Jeschke M, Mendoza Schulz A, Hoch G, Bartels M, Vogt G, Garnham CW, Yawo H, Fukazawa Y, Augustine GJ, Bamberg E, Kugler S, Salditt T, de Hoz L, Strenzke N, Moser T (2014) Optogenetic stimulation of the auditory pathway. J Clin Invest 124:1114-1129

Kim JM, Wu S, Tomasiak T, Mergel C, Winter MN, Stiller S, Robles-Colmanares Y, Stroud RM, Tampé R, Craik CS, Cheng Y (2014) Subnanometer cryo-EM structure of a nucleotide free heterodimeric ABC exporter. Nature:doi:10.1038/nature13872.

Knuppertz L, Hamann A, Pampaloni F, Stelzer EHK, Osiewacz HD (2014) Identification of autophagy as a longevity-assurance mechanism in the aging model Podospora anserina. Autophagy 10:822-834

Kohl-Landgraf J, Buhr F, Lefrancois D, Mewes JM, Schwalbe H, Dreuw A, Wachtveitl J (2014) Mechanism of the photoinduced uncaging reaction of puromycin protected by a 6-nitroveratryloxycarbonyl group. J Am Chem Soc 136:3430-3438

Kolodziej S, Kuvardina ON, Oellerich T, Herglotz J, Backert I, Kohrs N, Buscato E, Wittmann SK, Salinas-Riester G, Bonig H, Karas M, Serve H, Proschak E, Lausen J (2014) PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation. Nat Commun 5, article 3995

Koster S, van Pee K, Hudel M, Leustik M, Rhinow D, Kühlbrandt W, Chakraborty T, Yildiz O (2014) Crystal structure of listeriolysin O reveals molecular details of oligomerization and pore formation. Nat Commun 5, article 3690

Kühlbrandt W (2014) The Resolution Revolution. Science 343:1443-1444

Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JCH, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, Ameln vS, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C (2014) Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features. Nat Genet doi:10.1038/ng.3103

Lopez-Mosqueda J, Dikic I (2014) Deciphering functions of branched ubiquitin chains. Cell 157:767-769

Lu JH, He LQ, Behrends C, Araki M, Araki K, Wang QJ, Catanzaro JM, Friedman SL, Zong WX, Fiel MI, Li M, Yue ZY (2014) NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity. Nat Commun 5, article 3920

Manavski Y, Boon RA, Dimmeler S (2014) Vascular niche controls organ regeneration. Circ Res 114:1077-1079

Michalik KM, You X, Manavski Y, Doddaballapur A, Zornig M, Braun T, John D, Ponomareva Y, Chen W, Uchida S, Boon RA, Dimmeler S (2014) Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth. Circ Res 114:1389-1397

Müller-McNicoll M, Neugebauer KM (2014) Good cap/bad cap: how the cap-binding complex determines RNA fate. Nat Struct Mol Biol 21:9-12

Nair-Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y, Banerjee M, Overholtzer M, Roche PA, Tampé R, Brown BD, Amsen D, Whiteheart SW, Blander JM (2014) TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation. Cell 158 506–521

Pfanner N, van der Laan M, Amati P, Capaldi RA, Caudy AA, Chacinska A, Darshi M, Deckers M, Hoppins S, Icho T, Jakobs S, Ji J, Kozjak-Pavlovic V, Meisinger C, Odgren PR, Park SK, Rehling P, Reichert AS, Sheikh MS, Taylor SS, Tsuchida N, van der Bliek AM, van der Klei IJ, Weissman JS, Westermann B, Zha J, Neupert W, Nunnari J (2014) Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol 204:1083-1086

Rogov V, Dötsch V, Johansen T, Kirkin V (2014) Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol Cell 53:167-178

Schäffer V, Akutsu M, Olma MH, Gomes LC, Kawasaki M, Dikic I (2014) Binding of OTULIN to the PUB domain of HOIP controls NF-κB signaling. Mol Cell 54:349–361

Singh D, Pohl C (2014) Coupling of rotational cortical flow, asymmetric midbody positioning, and spindle rotation mediates dorsoventral axis formation in C. elegans. Dev Cell 28:253-267

Sripakdeevong P, Cevec M, Chang AT, Erat MC, Ziegeler M, Zhao Q, Fox GE, Gao X, Kennedy SD, Kierzek R, Nikonowicz EP, Schwalbe H, Sigel RKO, Turner DH, Das R (2014) Structure determination of noncanonical RNA motifs guided by (1)H NMR chemical shifts. Nat Methods 11:413-416

Stehle J, Silvers R, Werner K, Chatterjee D, Gande S, Scholz F, Dutta A, Wachtveitl J, Klein-Seetharaman J, Schwalbe H (2014) Characterization of the simultaneous decay kinetics of metarhodopsin states II and III in rhodopsin by solution-state NMR spectroscopy. Angew Chem Int Edit 53:2078-2084

Stehle J, Silvers R, Werner K, Chatterjee D, Gande S, Scholz F, Dutta A, Wachtveitl J, Klein-Seetharaman J, Schwalbe H (2014) Solution NMR characterization of simultaneous meta II and meta III decay kinetics in rhodopsin. Angew Chem Int Edit 126:2110–2116

Steinert HS, Schafer F, Jonker HR, Heckel A, Schwalbe H (2014) Influence of the absolute configuration of NPE-caged cytosine on DNA single base pair stability. Angew Chem Int Edit 53:1072-1075

Stellos K, Dimmeler S (2014) Vascular microRNAs: from disease mechanisms to therapeutic targets. Cric Res 114:3-4

Stolz A, Ernst A, Dikic I (2014) Cargo recognition and trafficking in selective autophagy. Nat Cell Biol 16:495-501

Tucci P, Agostini M, Grespi F, Markert EK, Terrinoni A, Vousden KH, Muller PAJ, Dötsch V, Kehrloesser S, Sayan BS, Giaccone G, Lowe SW, Takahashi N, Vandenabeele P, Knight RA, Levine AJ, Melino G (2014) Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer (vol 109, pg 15312, 2012). Proc Natl Acad Sci USA 111:2855-2855

Urban M, Kleefen A, Mukherjee N, Seelheim P, Windschiegl B, Vor der Bruggen M, Kocer A, Tampé R (2014) Highly parallel transport recordings on a membrane-on-nanopore chip at single molecule resolution. Nano Lett 14:1674-1680

Vermeer JEM, von Wangenheim D, Barberon M, Lee Y, Stelzer EHK, Maizel A, Geldner N (2014) A spatial accommodation by neighboring cells is required for organ initiation in arabidopsis. Science 343:178-183

Worzfeld T, Swiercz JM, Senturk A, Genz B, Korostylev A, Deng SH, Xia JJ, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S (2014) Genetic dissection of plexin signaling in vivo. Proc Natl Acad Sci USA 111:2194-2199

 

2013

Assmus B, Walter DH, Seeger FH, Leistner DM, Steiner J, Ziegler I, Lutz A, Khaled W, Klotsche J, Tonn T, Dimmeler S, Zeiher AM (2013) Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: The CELLWAVE Randomized Clinical Trial. Jama-Journal of the American Medical Association 309:1622-1631.

Bono F, De Smet F, Herbert C, De Bock K, Georgiadou M, Fons P, Tjwa M, Alcouffe C, Ny A, Bianciotto M, Jonckx B, Murakami M, Lanahan AA, Michielsen C, Sibrac D, Dol-Gleizes F, Mazzone M, Zacchigna S, Herault JP, Fischer C, Rigon P, Ruiz de Almodovar C, Claes F, Blanc I, Poesen K, Zhang J, Segura I, Gueguen G, Bordes MF, Lambrechts D, Broussy R, van de Wouwer M, Michaux C, Shimada T, Jean I, Blacher S, Noel A, Motte P, Rom E, Rakic JM, Katsuma S, Schaeffer P, Yayon A, Van Schepdael A, Schwalbe H, Gervasio FL, Carmeliet G, Rozensky J, Dewerchin M, Simons M, Christopoulos A, Herbert JM, Carmeliet P (2013) Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell 23:477-488.

Boon RA, Iekushi K, Lechner S, Seeger T, Fischer A, Heydt S, Kaluza D, Treguer K, Carmona G, Bonauer A, Horrevoets AJG, Didier N, Girmatsion Z, Biliczki P, Ehrlich JR, Katus HA, Muller OJ, Potente M, Zeiher AM, Hermeking H, Dimmeler S (2013) MicroRNA-34a regulates cardiac ageing and function. Nature 495:107-110.

Crosetto N, Mitra A, Silva MJ, Bienko M, Dojer N, Wang Q, Karaca E, Chiarle R, Skrzypczak M, Ginalski K, Pasero P, Rowicka M, Dikic I (2013) Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing. Nature Methods 10:361-NIL_119.

De Rosa S, Seeger FH, Honold J, Fischer-Rasokat U, Lehmann R, Fichtlscherer S, Schachinger V, Dimmeler S, Zeiher AM, Assmus B (2013) Procedural safety and predictors of acute outcome of intracoronary administration of progenitor cells in 775 consecutive procedures performed for acute myocardial infarction or chronic heart failure. Circulation 6:44-51.

Denic V, Dötsch V, Sinning I (2013) Endoplasmic Reticulum Targeting and Insertion of Tail-Anchored Membrane Proteins by the GET Pathway. Csh Perspect Biol 5.

Dimmeler S, Nicotera P (2013) MicroRNAs in age-related diseases. EMBO Mol Med 5:180-190.

Fischer F, Weil A, Hamann A, Osiewacz HD (2013) Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain. Nat Commun 4, article number: 1397.

Guan JY, Keizers PHJ, Liu WM, Lohr F, Skinner SP, Heeneman EA, Schwalbe H, Ubbink M, Siegal G (2013) Small-molecule binding sites on proteins established by paramagnetic NMR spectroscopy. Journal of the American Chemistry Society 135:5859-5868.

Hansel R, Lohr F, Trantirek L, Dötsch V (2013) High-resolution insight into G-Overhang architecture. Journal of the American Chemistry Society 135:2816-2824.

Herbert C, Schieborr U, Saxena K, Juraszek J, De Smet F, Alcouffe C, Bianciotto M, Saladino G, Sibrac D, Kudlinzki D, Sreeramulu S, Brown A, Rigon P, Herault JP, Lassalle G, Blundell TL, Rousseau F, Gils A, Schymkowitz J, Tompa P, Herbert JM, Carmeliet P, Gervasio FL, Schwalbe H, Bono F (2013) Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell 23:489-501.

Kittelmann M, Liewald JF, Hegermann J, Schultheiss C, Brauner M, Steuer Costa W, Wabnig S, Eimer S, Gottschalk A (2013) In vivo synaptic recovery following optogenetic hyperstimulation. P Natl Acad Sci USA 110:E2007-2016.

Laboria N, Wieneke R, Tampé R (2013) Control of nanomolar interaction and in situ assembly of proteins in four dimensions by light. Angew Chem Int Edit 52:848-853.

Lorenz-Fonfria VA, Resler T, Krause N, Nack M, Gossing M, Fischer von Mollard G, Bamann C, Bamberg E, Schlesinger R, Heberle J (2013) Transient protonation changes in channelrhodopsin-2 and their relevance to channel gating. P Natl Acad Sci USA 110:E1273-1281.

Lucas M, Kenobi K, von Wangenheim D, Voss U, Swarup K, De Smet I, Van Damme D, Lawrence T, Peret B, Moscardi E, Barbeau D, Godin C, Salt D, Guyomarc'h S, Stelzer EHK, Maizel A, Laplaze L, Bennett MJ (2013) Lateral root morphogenesis is dependent on the mechanical properties of the overlaying tissues. P Natl Acad Sci USA 110:5229-5234.

Michaelis UR, Chavakis E, Kruse C, Jungblut B, Kaluza D, Wandzioch K, Manavski Y, Heide H, Santoni MJ, Potente M, Eble JA, Borg JP, Brandes RP (2013) The polarity protein scrib is essential for directed endothelial cell migration. Circ Res 112:924-U159.

Neumann-Verhoefen MK, Neumann K, Bamann C, Radu I, Heberle J, Bamberg E, Wachtveitl J (2013) Ultrafast infrared spectroscopy on channelrhodopsin-2 reveals efficient energy transfer from the retinal chromophore to the protein.
J Am Chem Soc 135:6968-6976.

Ngo JT, Schuman EM, Tirrell DA (2013) Mutant methionyl-tRNA synthetase from bacteria enables site-selective N-terminal labeling of proteins expressed in mammalian cells. P Natl Acad Sci USA 110:4992-4997.

Preiss L, Klyszejko AL, Hicks DB, Liu J, Fackelmayer OJ, Yildiz O, Krulwich TA, Meier T (2013) The c-ring stoichiometry of ATP synthase is adapted to cell physiological requirements of alkaliphilic Bacillus pseudofirmus OF4. P Natl Acad Sci USA 110:7874-7879.

Reining A, Nozinovic S, Schlepckow K, Buhr F, Furtig B, Schwalbe H (2013) Three-state mechanism couples ligand and temperature sensing in riboswitches. Nature 499:355-U135.

Rhodes CJ, Wharton J, Boon RA, Roexe T, Tsang H, Wojciak-Stothard B, Chakrabarti A, Howard LS, Gibbs JSR, Lawrie A, Condliffes R, Elliot CA, Kielys DG, Huson L, Ghofrani HA, Tiede H, Schermuly R, Zeihers AM, Dimmeler S, Wilkins MR (2013) Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension. Am J Respir Crit Care Med 187:294-302.

Schulz S, Iglesias-Cans M, Krah A, Yildiz O, Leone V, Matthies D, Cook GM, Faraldo-Gomez JD, Meier T (2013) A new type of Na+-driven ATP synthase membrane rotor with a Two-Carboxylate Ion-Coupling motif. Plos Biol 11: article number e1001596.

Schlepckow K, Schwalbe H (2013) Molecular Mechanism of Prion Protein Oligomerization at Atomic Resolution. Angew Chem Int Edit Article. Published online: 9 August 2013, DOI: 10.1002/anie.201305184.

Spindler PE, Glaser SJ, Skinner TE, Prisner TF (2013) Broadband Inversion PELDOR spectroscopy with partially adiabatic shaped pulses. Angew Chem Int Edit 52:3425-3429.

Staudt H, Hoesl MG, Dreuw A, Serdjukow S, Oesterhelt D, Budisa N, Wachtveitl J, Grininger M (2013) Directed manipulation of a flavoprotein photocycle. Angew Chem Int Edit 52:8463-8466.

Steinert HS, Schäfer F, Jonker HRA, Heckel A, Schwalbe H (2013) Influence of the absolute configuration of NPE-caged cytosine on DNA single base pair stability. Angew Chem Int Edit, DOI: 10.1002/anie.201307852, published online 11 December 2013.

Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese R, Simons K, Krogan NJ, Ernst R (2013) A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Mol Cell 51:519-530.

Wilk L, Grunwald M, Liao PN, Walla PJ, Kühlbrandt W (2013) Direct interaction of the major light-harvesting complex II and PsbS in nonphotochemical quenching. P Natl Acad Sci USA 110:5452-5456.

Yu YD, Heidel B, Parapugna TL, Wenderhold-Reeb S, Song B, Schonherr H, Grininger M, Nöll G (2013) The flavoprotein dodecin as a redox probe for electron transfer through DNA. Angew Chem Int Edit 52:4950-4953.

  

2012
Althoff T, Davies KM, Schulze S, Joos F, Kühlbrandt W (2012) GRecon: a method for the lipid reconstitution of membrane proteins. Angew Chem Int Edit 51:8343-7

Belgnaoui SM, Paz S, Samuel S, Goulet ML, Sun Q, Kikkert M, Iwai K, Dikic I, Hiscott J, Lin R (2012) Linear Ubiquitination of NEMO Negatively Regulates the Interferon Antiviral Response through Disruption of the MAVS-TRAF3 Complex. Cell Host & Microbe 12:211-22

Brieke C, Rohrbach F, Gottschalk A, Mayer G, Heckel A (2012) Light-controlled tools. Angew Chem Int Edit 51:8446-76

Cajigas IJ, Tushev G, Will TJ, Dieck ST, Fuerst N, Schuman EM (2012) The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging. Neuron 74:453-466

Davies KM, Anselmi C, Wittig I, Faraldo-Gomez JD, Kühlbrandt W (2012) Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae. P Natl Acad Sci USA 109:13602-7

Eicher T, Cha HJ, Seeger MA, Brandstatter L, El-Delik J, Bohnert JA, Kern WV, Verrey F, Grutter MG, Diederichs K, Pos KM (2012) Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. P Natl Acad Sci USA 109:5687-92

Fischer F, Hamann A, Osiewacz HD (2012) Mitochondrial quality control: an integrated network of pathways. Trends Biochem Sci 37:284-292

Fromel T, Jungblut B, Hu J, Trouvain C, Barbosa-Sicard E, Popp R, Liebner S, Dimmeler S, Hammock BD, Fleming I (2012) Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols. P Natl Acad Sci USA 109:9995-10000

Fulda S, Rajalingam K, Dikic I (2012) Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications. EMBO Mol Med 4:545-556

Gao Y, Meyer B, Sokolova L, Zwicker K, Karas M, Brutschy B, Peng GH, Michel H (2012) Heme-copper terminal oxidase using both cytochrome c and ubiquinol as electron donors. P Natl Acad Sci USA 109:3275-3280

Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R (2012) Caged glutathione: triggering protein interaction by light. Angew Chem Int Edit 51:3960-3

Hakulinen J, Klyszejko AL, Hoffmann J, Eckhardt-Strelau L, Brutschy B, Vonck J, Meier T (2012) Structural study on the architecture of the bacterial ATP synthase Fo motor. P Natl Acad Sci USA 109:E2050-6

Heide H, Bleier L, Steger M, Ackermann J, Drose S, Schwamb B, Zornig M, Reichert AS, Koch I, Wittig I, Brandt U (2012) Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex. Cell Metab 16:538-549

Hergenreider E, Heydt S, Treguer K, Boettger T, Horrevoets AJG, Zeiher AM, Scheffer MP, Frangakis AS, Yin XK, Mayr M, Braun T, Urbich C, Boon RA, Dimmeler S (2012) Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol 14:249-256

Husson SJ, Steuer Costa W, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM, Lu H, Gottschalk A (2012) Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors. Curr Biol 22:1-10

Imre G, Heering J, Takeda AN, Husmann M, Thiede B, Heringdorf DMZ, Green DR, van der Goot FG, Sinha B, Dötsch V, Rajalingam K (2012) Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis. EMBO J 31:2615-2628

Kovacevic I, Hu J, Siehoff-Icking A, Opitz N, Griffin A, Perkins AC, Munn AL, Müller-Esterl W, Popp R, Fleming I, Jungblut B, Hoffmeister M, Oess S (2012) The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development. EMBO J 31:3309-3322

Lieblein AL, Buck J, Schlepckow K, Fürtig B, Schwalbe H (2012) Time-resolved NMR spectroscopic studies of DNA i-Motif folding reveal kinetic partitioning. Angew Chem Int Edit 51:250-253

Lieblein AL, Krämer M, Dreuw A, Fürtig B, Schwalbe H (2012) The nature of hydrogen bonds in Cytidine···H+···Cytidine DNA base pairs. Angew Chem Int Edit 51:4067-4070

Luce K, Osiewacz HD (2012) Increasing organismal healthspan by enhancing mitochondrial protein quality control. Nat Cell Biol 14:220

Nishino Y, Eltsov M, Joti Y, Ito K, Takata H, Takahashi Y, Hihara S, Frangakis AS, Imamoto N, Ishikawa T, Maeshima K (2012) Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. EMBO J 31:1644-53

Oberoi TK, Dogan T, Hocking JC, Scholz RP, Mooz J, Anderson CL, Karreman C, Heringdorf DMZ, Schmidt G, Ruonala M, Namikawa K, Harms GS, Carpy A, Macek B, Koster RW, Rajalingam K (2012) IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J 31:14-28

Pogoryelov D, Klyszejko AL, Krasnoselska GO, Heller EM, Leone V, Langer JD, Vonck J, Müller DJ, Faraldo-Gómez JD, Meier T (2012) Engineering rotor ring stoichiometries in the ATP synthase. P Natl Acad Sci USA 109:E1599-E1608

Rossier O, Octeau V, Sibarita JB, Leduc C, Tessier B, Nair D, Gatterdam V, Destaing O, Albiges-Rizo C, Tampé R, Cognet L, Choquet D, Lounis B, Giannone G (2012) Integrins β1 and β3 display distinct dynamic nanoscale organizations inside focal adhesions. Nat Cell Biol 14:1057 - 1067

Ruzzenente B, Metodiev MD, Wredenberg A, Bratic A, Park CB, Camara Y, Milenkovic D, Zickermann V, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Brandt U, Stewart JB, Gustafsson CM, Larsson NG (2012) LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs. EMBO J 31:443-456

Saibil HR, Seybert A, Habermann A, Winkler J, Eltsov M, Perkovic M, Castano-Diez D, Scheffer MP, Haselmann U, Chlanda P, Lindquist S, Tyedmers J, Frangakis AS (2012) Heritable yeast prions have a highly organized three-dimensional architecture with interfiber structures. P Natl Acad Sci USA 109:14906-14911

Sandilands E, Serrels B, McEwan DG, Morton JP, Macagno JP, McLeod K, Stevens C, Brunton VG, Langdon WY, Vidal M, Sansom OJ, Dikic I, Wilkinson S, Frame MC (2012) Autophagic targeting of Src promotes cancer cell survival following reduced FAK signallin. Nat Cell Biol 14:51-U76

Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S (2012) RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans. P Natl Acad Sci USA 109:18944-18949

Schlegel K, Leone V, Faraldo-Gómez JD, Muller V (2012) Promiscuous archaeal ATP synthase concurrently coupled to Na(+) and H(+) translocation. P Natl Acad Sci USA 109:947-952

Silvers R, Sziegat F, Tachibana H, Segawa S, Whittaker S, Gunther UL, Gabel F, Huang JR, Blackledge M, Wirmer-Bartoschek J, Schwalbe H (2012) Modulation of structure and dynamics by disulfide bond formation in unfolded states. Journal of the American Chemistry Society 134:6846-6854.

Symersky J, Pagadala V, Osowski D, Krah A, Meier T, Faraldo-Gomez JD, Mueller DM (2012) Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation. Nat Struct Mol Biol 19:485-U40

Tucci P, Agostini M, Grespi F, Markert EK, Terrinoni A, Vousden KH, Muller PAJ, Dötsch V, Kehrloesser S, Sayan BS, Giaccone G, Lowe SW, Takahashi N, Vandenabeele P, Knight RA, Levine AJ, Melino G (2012) Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. P Natl Acad Sci USA 109:15312-15317

van Wijk SJL, Fiskin E, Putyrski M, Pampaloni F, Hou J, Wild P, Kensche T, Grecco HE, Bastiaens P, Dikic I (2012) Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells. Molecular Cell:in press. doi 10.1016/j.molcel.2012.06.017

Wei RS, Gatterdam V, Wieneke R, Tampé R, Rant U (2012) Stochastic sensing of proteins with receptor-modified solid-state nanopores. Nat Nanotechnol 7:257-263

 

2011

Barthelme D, Dinkelaker S, Albers SV, Londei P, Ermler U, Tampé R (2011) Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1. P Natl Acad Sci USA 108:3228-3233

Davies KM, Strauss M, Daum B, Kief JH, Osiewacz HD, Rycovska A, Zickermann V, Kühlbrandt W (2011) Macromolecular organization of ATP synthase and complex I in whole mitochondria. P Natl Acad Sci USA 108:14121-14126

Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V (2011) DNA damage in oocytes induces a switch of the quality control factor TAp63± from dimer to tetramer. Cell 144:566-576

Dröse S, Krack S, Sokolova L, Zwicker K, Barth HD, Morgner N, Heide H, Steger M, Nubel E, Zickermann V, Kerscher S, Brutschy B, Radermacher M, Brandt U (2011) Functional dissection of the proton pumping modules of mitochondrial complex I. PLoS Biol 9:Article Number: e1001128

Grabbe C, Husnjak K, Dikic I (2011) The spatial and temporal organization of ubiquitin networks. Nat Rev Mol Cell Biol 12:295-307

Herget M, Baldauf C, Scholz C, Parcej D, Wiesmuller KH, Tampé R, Abele R, Bordignon E (2011) Conformation of peptides bound to the transporter associated with antigen processing (TAP). P Natl Acad Sci USA 108:1349-1354

Ikeda F, Deribe YL, Skanland SS, Stieglitz B, Grabbe C, Franz-Wachtel M, van Wijk SJL, Goswami P, Nagy V, Terzic J, Tokunaga F, Androulidaki A, Nakagawa T, Pasparakis M, Iwai K, Sundberg JP, Schaefer L, Rittinger K, Macek B, Dikic I (2011) SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappa B activity and apoptosis. Nature 471:637-U120

Jonker HRA, Baumann S, Wolf A, Schoof S, Hiller F, Schulte KW, Kirschner KN, Schwalbe H, Arndt HD (2011) NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew Chem Int Edit 50:3308-3312

Kim SA, Tai CY, Mok LP, Mosser EA, Schuman EM (2011) Calcium-dependent dynamics of cadherin interactions at cell-cell junctions. P Natl Acad Sci USA 108:9857-9862

Kleinlogel S, Feldbauer K, Dempski RE, Fotis H, Wood PG, Bamann C, Bamberg E (2011) Ultra light-sensitive and fast neuronal activation with the Ca(2+)-permeable channelrhodopsin CatCh. Nat Neurosci 14:513-U152

Kleinlogel S, Terpitz U, Legrum B, Gokbuget D, Boyden ES, Bamann C, Wood PG, Bamberg E (2011) A gene-fusion strategy for stoichiometric and co-localized expression of light-gated membrane proteins. Nat Methods 8:1083-1088.
 

Krstić I, Hänsel R, Romainczyk O, Engels JW, Dötsch V, Prisner TF (2011) Long-range distance measurements on nucleic acids in cells by pulsed EPR spectroscopy. Angew Chem Int Edit 50:5070-5074

Kuipers JE, Coenen EA, Balgobind BV, Stary J, Baruchel A, de Haas V, de Bont E, Reinhardt D, Kaspers GJL, Cloos J, Danen-van Oorschot AA, den Boer ML, Marschalek R, Meyer C, Pieters R, Zwaan CM, van den Heuvel-Eibrink MM (2011) High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23). Blood 117:928-935

Kuster L, Grausenburger R, Fuka G, Kaindl U, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer LH, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grumayer R (2011) ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling. Blood 117:2658-2667

Lieblein AL, Buck J, Schlepckow K, Fürtig B, Schwalbe H (2011) Time-resolved NMR spectroscopic studies of DNA i-Motif folding reveal kinetic partitioning. Angew Chem Int Edit 51:250-253

Marinelli F, Kuhlmann SI, Grell E, Kunte HJ, Ziegler C, Faraldo-Gómez JD (2011) Evidence for an allosteric mechanism of substrate release from membrane-transporter accessory binding proteins. P Natl Acad Sci USA 108:E1285-E1292

McEwan DG, Dikic I (2011) The three musketeers of autophagy: phosphorylation, ubiquitylation and acetylation. Trends Cell Biol 21:195-201

Nozinovic S, Gupta P, Fürtig B, Richter C, Tullmann S, Duchardt-Ferner E, Holthausen MC, Schwalbe H (2011) Determination of the conformation of the 2 ' OH Group in RNA by NMR spectroscopy and DFT calculations. Angew Chem Int Edit 50:5397-5400

Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM (2011) Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell 144:67-78

Oschatz C, Maas C, Lecher B, Jansen T, Bjorkqvist J, Tradler T, Sedlmeier R, Burfeind P, Cichon S, Hammerschmidt S, Müller-Esterl W, Wuillemin WA, Nilsson G, Renne T (2011) Mast cells Increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity 34:258-268

Rahighi S, Dikic I (2011) Conformational flexibility and rotation of the RING domain in activation of cullin-RING ligases. Nat Struct Mol Biol 18:863-865

Reimer D, Pos KM, Thines M, Grun P, Bode HB (2011) A natural prodrug activation mechanism in nonribosomal peptide synthesis. Nat Chem Biol 7:888-890

Rinnenthal J, Buck J, Ferner J, Wacker A, Fürtig B, Schwalbe H (2011) Mapping the landscape of RNA dynamics with NMR spectroscopy. Accounts Chem Res 44:1292-1301
 

Schleiff E, Becker T (2011) Common ground for protein translocation: access control for mitochondria and chloroplasts. Nat Rev Mol Cell Biol 12:48-59

Sentürk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A (2011) Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature 472:356-U123

Sommer MS, Daum B, Gross LE, Weis BLM, Mirus O, Abram L, Maier UG, Kühlbrandt W, Schleiff E (2011) Chloroplast Omp85 proteins change orientation during evolution. P Natl Acad Sci USA 108:13841-13846

Stefer S, Reitz S, Wang F, Wild K, Pang YY, Schwarz D, Bomke J, Hein C, Löhr F, Bernhard F, Denic V, Dötsch V, Sinning I (2011) Structural basis for tzil-anchored membrane protein biogenesis by the Get3-receptor complex. Science 333:758-762

Stirman JN, Crane MM, Husson SJ, Wabnig S, Schultheis C, Gottschalk A, Lu H (2011) Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans. Nat Methods 8:153-U78

Sziegat F, Wirmer-Bartoschek J, Schwalbe H (2011) Characteristics of human lysozyme and its disease-related mutants in their unfolded states. Angew Chem Int Edit 50:5514-5518

Ullrich SJ, Hellmich UA, Ullrich S, Glaubitz C (2011) Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR. Nat Chem Biol 7:263-270

van Wijk SJL, Muller S, Dikic I (2011) Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair. Genes Dev 25:1763-1769

Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT (2011) Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin. P Natl Acad Sci USA 108:17504-17509

von der Hocht I, van Wonderen JH, Hilbers F, Angerer H, MacMillan F, Michel H (2011) Interconversions of P and F intermediates of cytochrome c oxidase from Paracoccus denitrificans. P Natl Acad Sci USA 108:3964-3969

Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, Brady NR, Richter B, Korac J, Waidmann O, Choudhary C, Dötsch V, Bumann D, Dikic I (2011) Phosphorylation of the autophagy receptor optineurin restricts salmonella growth. Science 333:228-233

Yonehara K, Balint K, Noda M, Nagel G, Bamberg E, Roska B (2011) Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit. Nature 469:407-410

 

 

 

2010

Ackermann D, Schmidt TL, Hannam JS, Purohit CS, Heckel A, Famulok M (2010) A double-stranded DNA rotaxane. Nat Nanotechnol 5:436-442

Baldauf C, Schrodt S, Herget M, Koch J, Tampé R (2010) Single residue within the antigen translocation complex TAP controls the epitope repertoire by stabilizing a receptive conformation. P Natl Acad Sci USA 107:9135-9140

Bienko M, Green CM, Sabbioneda S, Crosetto N, Matic I, Hibbert RG, Begovic T, Niimi A, Mann M, Lehmann AR, Dikic I (2010) Regulation of translesion synthesis DNA polymerase h by monoubiquitination. Mol Cell 37:396-407

Bomar MG, D'Souza S, Bienko M, Dikic I, Walker GC, Zhou P (2010) Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases i and Rev1. Mol Cell 37:408-417

Bursen A, Schwabe K, Ruster B, Henschler R, Ruthardt M, Dingermann T, Marschalek R (2010) The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4. Blood 115:3570-3579

Buschmann S, Warkentin E, Xie H, Langer JD, Ermler U, Michel H (2010) The structure of cbb3 cytochrome oxidase provides insights into proton pumping. Science 329:327-329

Cherepanov AV, Glaubitz C, Schwalbe H (2010) High-resolution studies of uniformly 13C,15N-labeled RNA by solid-state NMR spectroscopy. Angew Chem Int Edit 49:4747-4750

Coutandin D, Ou HD, Lohr F, Dötsch V (2010) Tracing the protectors path from the germ line to the genome. P Natl Acad Sci USA 107:15318-15325

Deribe YL, Pawson T, Dikic I (2010) Post-translational modifications in signal integration. Nat Struct Mol Biol 17:666-672

Dieterich DC, Hodas JJL, Gouzer G, Shadrin IY, Ngo JT, Triller A, Tirrell DA, Schuman EM (2010) In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nat Neurosci 13:897-U149

Duchardt-Ferner E, Weigand JE, Ohlenschlager O, Schtnidtke SR, Suess B, Wöhnert J (2010) Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew Chem Int Edit 49:6216-6219

Gipson P, Mills DJ, Wouts R, Grininger M, Vonck J, Kühlbrandt W (2010) Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy. P Natl Acad Sci USA 107:9164-9

Grunwald C, Schulze K, Reichel A, Weiss VU, Blaas D, Piehler J, Wiesmüller KH, Tampé R (2010) In situ assembly of macromolecular complexes triggered by light. P Natl Acad Sci USA 107:6146-6151

Haglund K, Nezis IP, Lemus D, Grabbe C, Wesche J, Liestol K, Dikic I, Palmer R, Stenmark H (2010) Cindr interacts with anillin to control cytokinesis in drosophila melanogaster. Curr Biol 20:944-950

Hunte C, Zickermann V, Brandt U (2010) Functional modules and structural basis of conformational coupling in mitochondrial complex I. Science 329:448-451

Ikeda F, Crosetto N, Dikic I (2010) What determines the specificity and outcomes of ubiquitin signaling? Cell 143:677-681

Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EHK (2010) Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy. Nat Methods 7:637-U55

Lyubenova S, Maly T, Zwicker K, Brandt U, Ludwig B, Prisner TF (2010) Multifrequency pulsed electron paramagnetic resonance on metalloproteins. Accounts Chem Res 43:181-189

Maslennikov I, Klammt C, Hwang E, Kefala G, Okamura M, Esquivies L, Mors K, Glaubitz C, Kwiatkowski W, Jeon YH, Choe S (2010) Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. P Natl Acad Sci USA 107:10902-10907

Maslennikov I, Klammt C, Hwang E, Kefala G, Okamura M, Esquivies L, Mors K, Glaubitz C, Kwiatkowski W, Jeon YH, Choe S (2010) Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. P Natl Acad Sci USA 107:10902-10907

McEwan DG, Dikic I (2010) Not all autophagy membranes are created equal. Cell 141:564-566

O'Donoghue SI, Goodsell DS, Frangakis AS, Jossinet F, Laskowski RA, Nilges M, Saibil HR, Schafferhans A, Wade RC, Westhof E, Olson AJ (2010) Visualization of macromolecular structures. Nat Methods 7:S42-55

Parcej D, Tampé R (2010) ABC proteins in antigen translocation and viral inhibition. Nat Chem Biol 6:572-580

Pogoryelov D, Krah A, Langer JD, Yildiz O, Faraldo-Gomez JD, Meier T (2010) Microscopic rotary mechanism of ion translocation in the F-0 complex of ATP synthases. Nat Chem Biol 6:891-899

Preiss L, Yildiz O, Hicks DB, Krulwich TA, Meier T (2010) A new type of proton coordination in an F1Fo-ATP synthase rotor ring. PLoS Biol 8:10

Ratje AH, Loerke J, Mikolajka A, Brunner M, Hildebrand PW, Starosta AL, Donhofer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu YN, Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn CMT (2010) Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature 468:713-U143

Rutishauser U, Ross IB, Mamelak AN, Schuman EM (2010) Human memory strength is predicted by theta-frequency phase-locking of single neurons. Nature 464:903-907

Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T, Acker-Palmer A (2010) Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465:487-491

Schulze S, Koster S, Geldmacher U, van Scheltinga ACT, Kühlbrandt W (2010) Structural basis of Na+-independent and cooperative substrate/product antiport in CaiT. Nature 467:233-U129

Schwalbe H, Rinnenthal J (2010) Thermodynamics: The world is flat. Nat Chem Biol 6:312-313

Silvers R, Buhr F, Schwalbe H (2010) The Molecular Mechanism of Spider-Silk Formation. Angew Chem Int Edit 49:5410-5412

Sobhanifar S, Schneider B, Löhr F, Gottstein D, Ikeya T, Mlynarczyk K, Pulawski W, Ghoshdastider U, Kolinski M, Filipek S, Güntert P, Bernhard F, Dötsch V (2010) Structural investigation of the C-terminal catalytic fragment of presenilin 1. P Natl Acad Sci USA 107:9644-9649

Tai HC, Schuman EM (2010) Angelman syndrome: Finding the lost arc. Cell 140:608-610

Taylor AM, Dieterich DC, Ito HT, Kim SA, Schuman EM (2010) Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron 66:57-68

Vivanco I, Rohle D, Versele M, Iwanami A, Kuga D, Oldrini B, Tanaka K, Dang J, Kubek S, Palaskas N, Hsueh T, Evans M, Mulholland D, Wolle D, Rajasekaran S, Rajasekaran A, Liau LM, Cloughesy TF, Dikic I, Brennan C, Wu H, Mischel PS, Perera T, Mellinghoff IK (2010) The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation. P Natl Acad Sci USA 107:6459-6464

Wild P, Dikic I (2010) Mitochondria get a Parkin' ticket. Nat Cell Biol 12:104-106

 

2009

Abele R, Tampé R (2009) Peptide trafficking and translocation across membranes in cellular signaling and self-defense strategies. Curr Opin Cell Biol 21:508-515

Armistead J, Khatkar S, Meyer B, Mark BL, Patel N, Coghlan G, Lamont RE, Liu SB, Wiechert J, Cattini PA, Koetter P, Wrogemann K, Greenberg CR, Entian KD, Zelinski T, Triggs-Raine B (2009) Mutation of a Gene Essential for Ribosome Biogenesis, EMG1, Causes Bowen-Conradi Syndrome. Am J Hum Genet 84:728-739

Bohnsack MT, Martin R, Granneman S, Ruprecht M, Schleiff E, Tollervey D (2009) Prp43 Bound at Different Sites on the Pre-rRNA Performs Distinct Functions in Ribosome Synthesis. Mol Cell 36:583-592

Brandes M, Willimann K, Bioley G, Levy N, Eberl M, Luo M, Tampé R, Levy F, Romero P, Moser B (2009) Cross-presenting human gamma delta T cells induce robust CD8(+) alpha beta T cell responses. P Natl Acad Sci USA 106:2307-2312

Bredenbeck J, Ghosh A, Nienhuys HK, Bonn M (2009) Interface-specific ultrafast two-dimensional vibrational spectroscopy. Accounts Chem Res 42:1332-42

Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Kowarz E, Schneider B, Raff T, Reinhardt R, Gokbuget N, Hoelzer D, Thiel E, Marschalek R (2009) The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group. Blood 113:4011-4015

Busche AEL, Aranko AS, Talebzadeh-Farooji M, Bernhard F, Dötsch V, Iwai H (2009) Segmental Isotopic Labeling of a Central Domain in a Multidomain Protein by Protein Trans-Splicing Using Only One Robust DnaE Intein. Angew Chem Int Edit 48:6128-6131

Camargo SMR, Singer D, Makrides V, Huggel K, Pos KM, Wagner CA, Kuba K, Danilczyk U, Skovby F, Kleta R, Penninger JM, Verrey F (2009) Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations. Gastroenterology 136:872-882

Dikic I, Wakatsuki S, Walters KJ (2009) Ubiquitin-binding domains - from structures to functions. Nat Rev Mol Cell Biol 10:659-671

Feldbauer K, Zimmermann D, Pintschovius V, Spitz J, Bamann C, Bamberg E (2009) Channelrhodopsin-2 is a leaky proton pump. P Natl Acad Sci USA 106:12317-12322

Gerum C, Silvers R, Wirmer-Bartoschek J, Schwalbe H (2009) Unfolded-State Structure and Dynamics Influence the Fibril Formation of Human Prion Protein13. Angew Chem Int Edit 48:9452-9456

Grabbe C, Dikic I (2009) Functional roles of Ubiquitin-like domain (ULD) and Ubiquitin-binding domain (UBD) containing proteins. Chem Rev 109:1481-1494

Höller D, Dikic I (2009) Targeting the ubiquitin system in cancer therapy. Nature 458:438-444

Janes PW, Wimmer-Kleikamp SH, Frangakis AS, Treble K, Griesshaber B, Sabet O, Grabenbauer M, Ting AY, Saftig P, Bastiaens PI, Lackmann M (2009) Cytoplasmic Relaxation of Active Eph Controls Ephrin Shedding by ADAM10. PLoS Biol 7:17

Kirkin V, Lamark T, Sou Y, Bjorkoy G, Nunn J, Bruun J, Shvets E, Mc Ewan D, Clausen T, Wild P, Bilusic I, Theurillat JP, Overvatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T (2009) A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates. Mol Cell 33:505-516

Krauter J, Wagner K, Schafer I, Marschalek R, Meyer C, Heil G, Schaich M, Ehninger G, Niederwieser D, Krahl R, Buchner T, Sauerland C, Schlegelberger B, Dohner K, Dohner H, Schlenk RF, Ganser A (2009) Prognostic factors in adult patients up to 60 years old with acute myeloid leukemia and translocations of chromosome band 11q23: Individual patient data-based meta-analysis of the German Acute Myeloid Leukemia Intergroup. J Clin Oncol 27:3000-3006

Kuhner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castano-Diez D, Chen WH, Devos D, Guell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Bottcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC (2009) Proteome Organization in a Genome-Reduced Bacterium. Science 326:1235-1240

Luce K, Osiewacz HD (2009) Increasing organismal healthspan by enhancing mitochondrial protein quality control. Nat Cell Biol 11:852-U168

Lyubenova S, Maly T, Zwicker K, Brandt U, Ludwig B, Prisner TF (2009) Multifrequency pulsed electron paramagnetic resonance on metalloproteins. Accounts Chem Res 43:181-189

Marcia M, Ermler U, Peng GH, Michel H (2009) The structure of Aquifex aeolicus sulfide:quinone oxidoreductase, a basis to understand sulfide detoxification and respiration. P Natl Acad Sci USA 106:9625-9630

Matsuki Y, Maly T, Ouari O, Karoui H, Le Moigne F, Rizzato E, Lyubenova S, Herzfeld J, Prisner TF, Tordo P, Griffin RG (2009) Dynamic Nuclear Polarization with a Rigid Biradical. Angew Chem Int Edit 48:4996-5000

Meurer S, Pioch S, Pabst T, Opitz N, Schmidt PM, Beckhaus T, Wagner K, Matt S, Gegenbauer K, Geschka S, Karas M, Stasch JP, Schmidt H, Müller-Esterl W (2009) Nitric Oxide-Independent Vasodilator Rescues Heme-Oxidized Soluble Guanylate Cyclase From Proteasomal Degradation. Circ Res 105:33-U91

Oancea G, O'Mara ML, Bennett WFD, Tieleman DP, Abele R, Tampé R (2009) Structural arrangement of the transmission interface in the antigen ABC transport complex TAP. P Natl Acad Sci USA 106:5551-5556

Pogoryelov D, Yildiz O, Faraldo-Gomez JD, Meier T (2009) High-resolution structure of the rotor ring of a proton-dependent ATP synthase. Nat Struct Mol Biol 16:1068-U88

Poulopoulos A, Aramuni G, Meyer G, Soykan T, Hoon M, Papadopoulos T, Zhang MY, Paarmann I, Fuchs C, Harvey K, Jedlicka P, Schwarzacher SW, Betz H, Harvey RJ, Brose N, Zhang WQ, Varoqueaux F (2009) Neuroligin 2 Drives Postsynaptic Assembly at Perisomatic Inhibitory Synapses through Gephyrin and Collybistin. Neuron 63:628-642

Rabl R, Soubannier V, Scholz R, Vogel F, Mendl N, Vasiljev-Neumeyer A, Korner C, Jagasia R, Keil T, Baumeister W, Cyrklaff M, Neupert W, Reichert AS (2009) Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. J Cell Biol 185:1047-1063

Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R, Kensche T, Uejima T, Bloor S, Komander D, Randow F, Wakatsuki S, Dikic I (2009) Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation p1098. Cell 136:1098-1109

Renner S, van Otterlo WAL, Dominguez Seoane M, Mocklinghoff S, Hofmann B, Wetzel S, Schuffenhauer A, Ertl P, Oprea TI, Steinhilber D, Brunsveld L, Rauh D, Waldmann H (2009) Bioactivity-guided mapping and navigation of chemical space. Nat Chem Biol 5:585-592

Rhein V, Song XM, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Drose S, Brandt U, Savaskan E, Czech C, Gotz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. P Natl Acad Sci USA 106:20057-20062

Sabbioneda S, Green CM, Bienko M, Kannouche P, Dikic I, Lehmann AR (2009) Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization P Natl Acad Sci USA, pp E20-E20 (Letter) vol 106)

Sapra KT, Damaghi M, Koster S, Yildiz O, Kühlbrandt W, Muller DJ (2009) One beta Hairpin after the Other: Exploring Mechanical Unfolding Pathways of the Transmembrane beta-Barrel Protein OmpG. Angew Chem Int Edit 48:8306-8308

Schiemann O, Cekan P, Margraf D, Prisner TF, Sigurdsson ST (2009) Relative Orientation of Rigid Nitroxides by PELDOR: Beyond Distance Measurements in Nucleic Acids. Angew Chem Int Edit 48:3292-3295

Schleiff E, Tampé R (2009) Membrane proteins take center stage in Frankfurt. Nat Chem Biol 5:135-139

Schmidt MHH, Bicker F, Nikolic I, Meister J, Babuke T, Picuric S, Müller-Esterl W, Plate KH, Dikic I (2009) Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal. Nat Cell Biol 11:873-U245

Sreeramulu S, Gande SL, Gobel M, Schwalbe H (2009) Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90-Cdc37, a Kinome Chaperone-Cochaperone, by Triterpene Celastrol. Angew Chem Int Edit 48:5853-5855

Timinszky G, Till S, Hassa PO, Hothorn M, Kustatscher G, Nijmeijer B, Colombelli J, Altmeyer M, Stelzer EHK, Scheffzek K, Hottiger MO, Ladurner AG (2009) A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol 16:923-U41

 

 

2008

Beli P, Mascheroni D, Xu DL, Innocenti M (2008) WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2. Nat Cell Biol 10:849-857

Bertaso F, Zhang C, Scheschonka A, de Bock F, Fontanaud P, Marin P, Huganir R, Betz H, Bockaert J, Fagni L, Lerner-Natoli M (2008) PICK1 uncoupling from mGluR7a causes absence-like seizures. Nat Neurosci 11:940-948

Bloor S, Ryzhakov G, Wagner S, Jonathan P, Butler G, Smith DL, Krumbach R, Dikic I, Randow F (2008) Signal processing by its coil zipper domain activates IKK gamma. P Natl Acad Sci USA 105:1279-1284

Burgdorf S, Scholz C, Kautz A, Tampé R, Kurts C (2008) Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation. Nat Immunol 9:558-566

Connell SR, Topf M, Qin Y, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CMT (2008) A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nat Struct Mol Biol 15:910-915

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Eltsov M, MacLellan KM, Maeshima K, Frangakis AS, Dubochet J (2008) Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ. P Natl Acad Sci USA 105:19732-19737

Essmann CL, Martinez E, Geiger JC, Zimmer M, Traut MH, Stein V, Klein R, Acker-Palmer A (2008) Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nat Neurosci 11:1035-1043

Grabbe C, Dikic I (2008) Cell biology boing blobal on ubiquitin. Science 322:872-873

Hamm P, Helbing J, Bredenbeck J (2008) Two-dimensional infrared spectroscopy of photoswitchable peptides. Annu Rev Phys Chem 59:291-317

Harms JM, Wilson DN, Schluenzen F, Connell SR, Stachelhaus T, Zaborowska Z, Spahn CMT, Fucini P (2008) Translational regulation via L11: Molecular switches on the ribosome turned on and off by thiostrepton and micrococcin. Mol Cell 30:26-38

Husnjak K, Elsasser S, Zhang NX, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D, Dikic I (2008) Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 453:481-488

Ihalainen JA, Paoli B, Muff S, Backus EHG, Bredenbeck J, Woolley GA, Caflisch A, Hamm P (2008) a-Helix folding in the presence of structural constraints. P Natl Acad Sci USA 105:9588-9593

Jaskolla TW, Lehmann W-D, Karas M (2008) 4-Chloro-α-cyanocinnamic acid is an advanced, rationally designed MALDI matrix. P Natl Acad Sci USA 105:12200-12205

Koglin A, Lohr F, Bernhard F, Rogov VV, Frueh DP, Strieter ER, Mofid MR, Guntert P, Wagner G, Walsh CT, Marahiel MA, Dötsch V (2008) Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature 454:907-911

Liewald JF, Brauner M, Stephens GJ, Bouhours M, Schultheis C, Zhen M, Gottschalk A (2008) Optogenetic analysis of synaptic function. Nat Methods 5:895 - 902

Lopez JJ, Shukla AK, Reinhart C, Schwalbe H, Michel H, Glaubitz C (2008) The structure of the neuropeptide bradykinin bound to the human G-protein coupled receptor bradykinin B2 as determined by solid-state NMR spectroscopy. Angew Chem Int Edit 47:1668-1671

Madry C, Betz H, Geiger JRP, Laube B (2008) Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist. P Natl Acad Sci USA 105:12563-12568

Mahoney TR, Luo S, Round EK, Brauner M, Gottschalk A, Thomas JH, Nonet ML (2008) Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans. P Natl Acad Sci USA 105:16350-16355

Marafioti T, Paterson JC, Ballabio E, Reichard KK, Tedoldi S, Hollowood K, Dictor M, Hansmann ML, Pileri SA, Dyer MJ, Sozzani S, Dikic I, Shaw AS, Petrella T, Stein H, Isaacson PG, Facchetti F, Mason DY (2008) Novel markers of normal and neoplastic human plasmacytoid dendritic cells. Blood 111:3778-3792

Noren-Muller A, Wilk W, Saxena K, Schwalbe H, Kaiser M, Waldmann H (2008) Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis. Angew Chem Int Edit 47:5973-5977

Nosenko Y, Wiosna-Salyga G, Kunitski M, Petkova I, Singh A, Buma WJ, Thummel RP, Brutschy B, Waluk J (2008) Proton transfer with a twist? Femtosecond dynamics of 7-(2-pyridyl)-indole in condensed phase and in supersonic jets. Angew Chem Int Edit 47:6037-6040

Oreb M, Tews I, Schleiff E (2008) Policing Tic 'n' Toc, the doorway to chloroplasts. Trends Cell Biol 18:19-27

Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G (2008) Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov 7:738-745

Rasched G, Ackermann D, Schmidt TL, Broekmann P, Heckel A, Famulok M (2008) DNA minicircles with gaps for versatile functionalization. Angew Chem Int Edit 47:967-970

Reckel S, Sobhanifar S, Schneider B, Junge F, Schwarz D, Durst F, Lohr F, Guntert P, Bernhard F, Dötsch V (2008) Transmembrane segment enhanced labeling as a tool for the backbone assignment of alpha-helical membrane proteins. P Natl Acad Sci USA 105:8262-8267

Rubio M, Rinehart J, Krett B, Duvezin-Caubet AS, Reichert AS, Söll D, Alfonzo JD (2008) Mammalian mitochondira have the innate ability to import tRNAs by a mechanism distinct from protein import. P Natl Acad Sci USA 105:9186-9191

Schreiner P, Chen X, Husnjak K, Randles L, Zhang NX, Elsasser S, Finley D, Dikic I, Walters KJ, Groll M (2008) Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction. Nature 453:548-552

Seeger MA, von Ballmoos C, Eicher T, Brandstatter L, Verrey F, Diederichs K, Pos KM (2008) Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB. Nat Struct Mol Biol 15:199-205

Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P (2008) The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. P Natl Acad Sci USA 105:13339-13344

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2007

Al-Amoudi A, Diez DC, Betts MJ, Frangakis AS (2007) The molecular architecture of cadherins in native epidermal desmosomes. Nature 450:832-U8

Bredenbeck J, Helbing J, Nienhaus K, Nienhaus GU, Hamm P (2007) Protein ligand migration mapped by nonequilibrium 2D-IR exchange spectroscopy. P Natl Acad Sci USA 104:14243-14248

Buck J, Furtig B, Noeske J, Wohnert J, Schwalbe H (2007) Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution. P Natl Acad Sci USA 104:15699-15704

Connell SR, Takemoto C, Wilson DN, Wang HF, Murayama K, Terada T, Shirouzu M, Rost M, Schuler M, Giesebrecht J, Dabrowski M, Mielke T, Fucini P, Yokoyama S, Spahn CMT (2007) Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors. Mol Cell 25:751-764

Datta PP, Wilson DN, Kawazoe M, Swami NK, Kaminishi T, Sharma MR, Booth TM, Takemoto C, Fucini P, Yokoyama S, Agrawal RK (2007) Structural aspects of RbfA action during small ribosomal subunit. Mol Cell 28:434-445

Diller A, Roy E, Gast P, van Gorkom HJ, de Groot HJM, Glaubitz C, Jeschke G, Matysik J, Alia A (2007) N-15 photochemically induced dynamic nuclear polarization magic-angle spinning NMR analysis of the electron donor of photosystem II. P Natl Acad Sci USA 104:12767-12771

Faraldo-Gomez JD, Roux B (2007) On the importance of a funneled energy landscape for the assembly and regulation of multidomain Src tyrosine kinases. P Natl Acad Sci USA 104:13643-13648

Höller D, Hecker CM, Wagner S, Rogov V, Dötsch V, Dikic I (2007) E3-independent monoubiquitination of ubiquitin-binding proteins. Mol Cell 26:891-898

Hsu STD, Fucini P, Cabrita LD, Launay H, Dobson CM, Christodoulou J (2007) Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy. P Natl Acad Sci USA 104:16516-16521

Ihalainen JA, Bredenbeck J, Pfister R, Helbing J, Chi L, van Stokkum IHM, Woolley GA, Hamm P (2007) Folding and unfolding of a photoswitchable peptide from picoseconds to microseconds. P Natl Acad Sci USA 104:5383-5388

Kirkin V, Dikic I (2007) Role of ubiquitin- and Ubl-binding proteins in cell signaling. Curr Opin Cell Biol 19:199-205

Ludden MJW, Mulder A, Tampé R, Reinhoudt DN, Huskens J (2007) Molecular printboards as a general platform for protein immobilization: A supramolecular solution to nonspecific adsorption. Angew Chem Int Edit 46:4104-4107

Mookerjee RP, Wiesenthal A, Icking A, Hodges SJ, Davies NA, Schilling K, Sen S, Williams R, Novelli M, Müller-Esterl W, Jalan R (2007) Increased gene and protein expression of the novel eNOS regulatory protein NOSTRIN and a variant in alcoholic hepatitis. Gastroenterology 132:2533-2541

Radmark O, Werz O, Steinhilber D, Samuelsson B (2007) 5-Lipoxygenase: regulation of expression and enzyme activity. Trends Biochem Sci 32:332-341

Reese ML, Dakoji S, Bredt DS, Dötsch V (2007) The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a. Nat Struct Mol Biol 14:155-163

Sargin B, Choudhary C, Crosetto N, Schmidt MHH, Grundler R, Rensinghoff M, Thiessen C, Tickenbrock L, Schwable J, Brandts C, August B, Koschmieder S, Bandi SR, Duyster J, Berdel WE, Muller-Tidow C, Dikic I, Serve H (2007) Flt3-dependent transformation by inactivating c-Cbl mutations in AML. Blood 110:1004-1012

Scheckhuber CQ, Erjavec N, Tinazli A, Hamann A, Nystrom T, Osiewacz HD (2007) Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models. Nat Cell Biol 9:99-U129

Scheschonka A, Tang ZS, Betz H (2007) Sumoylation in neurons: nuclear and synaptic roles? Trends Neurosci 30:85-91

Schiemann O, Prisner TF (2007) Long-range distance determinations in biomacromolecules by EPR spectroscopy. Q Rev Biophys 40:1-53

Schmidt TL, Nandi CK, Rasched G, Parui PP, Brutschy B, Famulok M, Heckel A (2007) Polyamide struts for DNA architectures. Angew Chem Int Edit 46:4382-4384

Schwalbe H, Buck J, Furtig B, Noeske J, Wohnert J (2007) Structures of RNA switches: Insight into molecular recognition and tertiary structure. Angew Chem Int Edit 46:1212-1219

Segura I, Essmann CL, Weinges S, Acker-Palmer A (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat Neurosci 10:301-310

Sharma MR, Wilson DN, Datta PP, Barat C, Schluenzen F, Fucini P, Agrawal RK (2007) Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins. P Natl Acad Sci USA 104:19315-19320

Tinazli A, Piehler J, Beuttler M, Guckenberger R, Tampé R (2007) Native protein nanolithography that can write, read and erase. Nat Nanotechnol 2:220-225

Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, Watzke N, Wood PG, Bamberg E, Nagel G, Gottschalk A, Deisseroth K (2007) Multimodal fast optical interrogation of neural circuitry. Nature 446:633-639

 

 

 


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