CEF Top Publication List 2007-2019
2020
Gebel J, Tuppi M*, Chaikuad A, Hötte K, Schröder M, Schulz L, Löhr F, Gutfreund N, Finke F, Henrich E, Mezhyrova J, Lehnert R, Pampaloni F, Hummer G, Stelzer EHK, Knapp S, Dötsch V* (2020) p63 uses a switch-like mechanism to set the threshold for induction of apoptosis. Nat Chem Biol: published online 27 July 2020. http://dx.doi.org/10.1038/s41589-020-0600-3
Königs V, de Oliveira Freitas Machado C, Arnold B, Blümel N, Solovyeva A, Löbbert S, Schafranek M, Ruiz De Los Mozos I, Wittig I, McNicoll F*, Schulz MH, Müller-McNicoll M* (2020) SRSF7 maintains its homeostasis through the expression of Split-ORFs and nuclear body assembly. Nat Struct Mol Biol 27: 260-273. http://dx.doi.org/10.1038/s41594-020-0385-9
Kovalev K, Astashkin R, Gushchin I, Orekhov P, Volkov D, Zinovev E, Marin E, Rulev M, Alekseev A, Royant A, Carpentier P, Vaganova S, Zabelskii D, Baeken C, Sergeev I, Balandin T, Bourenkov G, Carpena X, Boer R, Maliar N, Borshchevskiy V, Buldt G, Bamberg E, Gordeliy V (2020) Molecular mechanism of light-driven sodium pumping. Nat Commun 11: 2137. http://dx.doi.org/10.1038/s41467-020-16032-y
Kovalev K, Volkov D, Astashkin R, Alekseev A, Gushchin I, Haro-Moreno JM, Chizhov I, Siletsky S, Mamedov M, Rogachev A, Balandin T, Borshchevskiy V, Popov A, Bourenkov G, Bamberg E, Rodriguez-Valera F, Buldt G, Gordeliy V (2020) High-resolution structural insights into the heliorhodopsin family. Proc Natl Acad Sci USA: published online 7 February 2020. http://dx.doi.org/10.1073/pnas.1915888117
Lieblein T, Zangl R, Martin J, Hoffmann J, Hutchison MJ, Stark T, Stirnal E, Schrader T, Schwalbe H, Morgner N* (2020) Structural rearrangement of amyloid-β upon inhibitor binding suppresses formation of Alzheimer disease related oligomers. eLife 9: http://dx.doi.org/10.7554/eLife.59306
Tascón I, Sousa JS, Corey RA, Mills DJ, Griwatz D, Aumüller N, Mikusevic V, Stansfeld PJ, Vonck J*, Hänelt I* (2020) Structural basis of proton-coupled potassium transport in the KUP family. Nat Commun 11: 626. http://dx.doi.org/10.1038/s41467-020-14441-7
von Wangenheim D, Banda J, Schmitz A, Boland J, Bishopp A, Maizel A, Stelzer EHK, Bennett M (2020) Early developmental plasticity of lateral roots in response to asymmetric water availability. Nat Plants 6: 73-77. http://dx.doi.org/10.1038/s41477-019-0580-z
Zimmermann I, Egloff P, Hutter CAJ, Kuhn BT, Brauer P, Newstead S, Dawson RJP, Geertsma ER*, Seeger MA* (2020) Generation of synthetic nanobodies against delicate proteins. Nat Protoc: published online 8 April 2020. http://dx.doi.org/10.1038/s41596-020-0304-x
2019
Alvarez-Castelao B, Schanzenbächer CT, Langer JD, Schuman EM (2019) Cell-type-specific metabolic labeling, detection and identification of nascent proteomes in vivo. Nat Protoc: published online 4 January 2019. http://dx.doi.org/10.1038/s41596-018-0106-6
Azimi Hashemi N, Bergs ACF, Schüler C, Scheiwe AR, Steuer Costa W, Bach M, Liewald JF, Gottschalk A (2019) Rhodopsin-based voltage imaging tools for use in muscles and neurons of Caenorhabditis elegans. Proc Natl Acad Sci USA: published online 1 August 2019. http://dx.doi.org/10.1073/pnas.1902443116
Bhaskara RM, Grumati P, Garcia-Pardo J, Kalayil S, Covarrubias-Pinto A, Chen W, Kudryashev M, Dikic I*, Hummer G* (2019) Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy. Nat Commun 10: 2370. http://dx.doi.org/10.1038/s41467-019-10345-3
Bhogaraju S*, Bonn F, Mukherjee R, Adams M, Pfleiderer MM, Galej WP, Matkovic V, Lopez-Mosqueda J, Kalayil S, Shin D, Dikic I* (2019) Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin-catalysed glutamylation. Nature: published online 22 July 2019. http://dx.doi.org/10.1038/s41586-019-1440-8
Blum TB, Hahn A, Meier T, Davies KM, Kühlbrandt W (2019) Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows. Proc Natl Acad Sci USA: published online 13 February 2019. http://dx.doi.org/10.1073/pnas.1816556116
Braner M, Koller N, Knauer J, Herbring V, Hank S, Wieneke R*, Tampé R* (2019) Optical control of the antigen translocation by synthetic photo-conditional viral inhibitors. Chem Sci 10: 2001-2005. http://dx.doi.org/10.1039/c8sc04863k
Bratanov D, Kovalev K, Machtens JP, Astashkin R, Chizhov I, Soloviov D, Volkov D, Polovinkin V, Zabelskii D, Mager T, Gushchin I, Rokitskaya T, Antonenko Y, Alekseev A, Shevchenko V, Yutin N, Rosselli R, Baeken C, Borshchevskiy V, Bourenkov G, Popov A, Balandin T, Buldt G, Manstein DJ, Rodriguez-Valera F, Fahlke C, Bamberg E, Koonin E, Gordeliy V (2019) Unique structure and function of viral rhodopsins. Nat Commun 10: 4939. http://dx.doi.org/10.1038/s41467-019-12718-0
Chang YN, Jaumann EA, Reichel K, Hartmann J, Oliver D, Hummer G*, Joseph B*, Geertsma ER* (2019) Structural basis for functional interactions in dimers of SLC26 transporters. Nat Commun 10: 2032. http://dx.doi.org/10.1038/s41467-019-10001-w
Cottilli P, Belda-Palazon B, Adkar-Purushothama CR, Perreault JP, Schleiff E, Rodrigo I, Ferrando A, Lison P (2019) Citrus exocortis viroid causes ribosomal stress in tomato plants. Nucleic Acids Res: published online 8 August 2019. http://dx.doi.org/10.1093/nar/gkz679
Diederichs T, Pugh G, Dorey A, Xing Y, Burns JR, Hung Nguyen Q, Tornow M, Tampé R*, Howorka S* (2019) Synthetic protein-conductive membrane nanopores built with DNA. Nat Commun 10: 5018. http://dx.doi.org/10.1038/s41467-019-12639-y
Dietz MS, Wehrheim SS, Harwardt MIE, Niemann HH, Heilemann M (2019) Competitive binding study revealing the influence of fluorophore labels on biomolecular interactions. Nano Lett: published online 17 October 2019. http://dx.doi.org/10.1021/acs.nanolett.9b03736
Faelber K*, Dietrich L, Noel JK, Wollweber F, Pfitzner AK, Mühleip A, Sanchez R, Kudryashev M, Chiaruttini N, Lilie H, Schlegel J, Rosenbaum E, Hessenberger M, Matthaeus C, Kunz S, von der Malsburg A, Noe F, Roux A, van der Laan M, Kühlbrandt W*, Daumke O* (2019) Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Nature: published online 10 July 2019. http://dx.doi.org/10.1038/s41586-019-1372-3
Fonkeu Y, Kraynyukova N, Hafner A-S, Kochen L, Sartori F, Schuman EM, Tchumatchenko T (2019) How mRNA localization and protein synthesis sites influence dendritic protein distribution and dynamics. Neuron: published online 23 July 2019. http://dx.doi.org/10.1016/j.neuron.2019.06.022
Fottner M, Brunner AD, Bittl V, Horn-Ghetko D, Jussupow A, Kaila VRI, Bremm A, Lang K (2019) Site-specific ubiquitylation and SUMOylation using genetic-code expansion and sortase. Nat Chem Biol 15: 276-284. http://dx.doi.org/10.1038/s41589-019-0227-4
Grammbitter GLC, Schmalhofer M, Karimi K, Shi Y-M, Schöner TA, Tobias NJ, Morgner N, Groll M, Bode HB (2019) An uncommon type II PKS catalyzes biosynthesis of aryl polyene pigments. J Am Chem Soc: published online 25 March 2019. http://dx.doi.org/10.1021/jacs.8b10776
Heumüller M, Glock C, Rangaraju V, Biever A, Schuman EM (2019) A genetically encodable cell-type-specific protein synthesis inhibitor. Nature Methods: http://dx.doi.org/10.1038/s41592-019-0468-x
Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant JY, Zarnack K*, König J*, Beli P* (2019) The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol 20: 216. http://dx.doi.org/10.1186/s13059-019-1814-0
Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R*, Moeller A* (2019) Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature: published online 17 July 2019. http://dx.doi.org/10.1038/s41586-019-1391-0
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jaattela M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E, Lanzetti L, De Zio D, Cecconi F (2019) Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nat Commun 10: 4176. http://dx.doi.org/10.1038/s41467-019-12094-9
Huber J, Obata M, Gruber J, Akutsu M, Löhr F, Rogova N, Güntert P, Dikic I, Kirkin V, Komatsu M, Dötsch V, Rogov VV (2019) An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy: published online 16 April 2019. http://dx.doi.org/10.1080/15548627.2019.1606637
Joseph B*, Jaumann EA, Sikora A, Barth K, Prisner TF, Cafiso DS (2019) In situ observation of conformational dynamics and protein ligand-substrate interactions in outer-membrane proteins with DEER/PELDOR spectroscopy. Nat Protoc: http://dx.doi.org/10.1038/s41596-019-0182-2
Kovalev K, Polovinkin V, Gushchin I, Alekseev A, Shevchenko V, Borshchevskiy V, Astashkin R, Balandin T, Bratanov D, Vaganova S, Popov A, Chupin V, Buldt G, Bamberg E*, Gordeliy V* (2019) Structure and mechanisms of sodium-pumping KR2 rhodopsin. Sci Adv 5: eaav2671. http://dx.doi.org/10.1126/sciadv.aav2671
Krchňáková Z, Thakur PK, Krausová M, Bieberstein N, Haberman N, Müller-McNicoll M, Staněk D (2019) Splicing of long non-coding RNAs primarily depends on polypyrimidine tract and 5′ splice-site sequences due to weak interactions with SR proteins. Nucleic Acids Res 47: 911-928. http://dx.doi.org/10.1093/nar/gky1147
Kreis P, Gallrein C, Rojas-Puente E, Mack TGA, Kroon C, Dinkel V, Willmes C, Murk K, Tom-Dieck S, Schuman EM, Kirstein J, Eickholt BJ (2019) ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans. Nat Commun 10: 486. http://dx.doi.org/10.1038/s41467-019-08420-w
Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M (2019) Deubiquitinase USP10 regulates Notch signaling in the endothelium. Science 364: 188-193. http://dx.doi.org/10.1126/science.aat0778
Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL, Kennedy MJ (2019) A photoactivatable botulinum neurotoxin for inducible control of neurotransmission. Neuron: published online 28 January 2019. http://dx.doi.org/10.1016/j.neuron.2019.01.002
Maciejko J, Kaur J, Becker-Baldus J, Glaubitz C (2019) Photocycle-dependent conformational changes in the proteorhodopsin cross-protomer Asp-His-Trp triad revealed by DNP-enhanced MAS-NMR. Proc Natl Acad Sci USA: published online 4 April 2019. http://dx.doi.org/10.1073/pnas.1817665116
Mas-Peiro S, Hoffmann J, Fichtlscherer S, Dorsheimer L, Rieger MA, Dimmeler S, Vasa-Nicotera M, Zeiher AM (2019) Clonal haematopoiesis in patients with degenerative aortic valve stenosis undergoing transcatheter aortic valve implantation. Eur Heart J: published online 3 September 2019. http://dx.doi.org/10.1093/eurheartj/ehz591
Merk D*, Sreeramulu S, Kudlinzki D, Saxena K, Linhard V, Gande SL, Hiller F, Lamers C, Nilsson E, Aagaard A, Wissler L, Dekker N, Bamberg K, Schubert-Zsilavecz M, Schwalbe H* (2019) Molecular tuning of farnesoid X receptor partial agonism. Nat Commun 10: 2915. http://dx.doi.org/10.1038/s41467-019-10853-2
Meyer C, Lopes BA, Caye-Eude A, Cave H, Arfeuille C, Cuccuini W, Sutton R, Venn NC, Oh SH, Tsaur G, Escherich G, Feuchtinger T, Kosasih HJ, Khaw SL, Ekert PG, Pombo-de-Oliveira MS, Bidet A, Djahanschiri B, Ebersberger I, Zaliova M, Zuna J, Zermanova Z, Juvonen V, Grumayer RP, Fazio G, Cazzaniga G, Larghero P, Emerenciano M, Marschalek R (2019) Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions. Leukemia: published online 21 March 2019. http://dx.doi.org/10.1038/s41375-019-0451-7
Mirtschink P, Bischof C, Pham MD, Sharma R, Khadayate S, Rossi G, Fankhauser N, Traub S, Sossalla S, Hagag E, Berthonneche C, Sarre A, Stehr SN, Grote P, Pedrazzini T, Dimmeler S, Krek W, Krishnan J (2019) Inhibition of the HIF1alpha-induced cardiospecific HERNA1 eRNA protects from heart disease. Circulation: published online 29 March 2019. http://dx.doi.org/10.1161/circulationaha.118.036769
Murphy BJ, Klusch N, Langer J, Mills DJ, Yildiz O, Kühlbrandt W (2019) Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. Science 364: eaaw9128. http://dx.doi.org/10.1126/science.aaw9128
Nishimura T, Gecht M, Covino R, Hummer G, Surma MA, Klose C, Arai H, Kono N, Stefan CJ (2019) Osh proteins control nanoscale lipid organization necessary for PI(4,5)P2 synthesis. Mol Cell: published online 8 August 2019. http://dx.doi.org/10.1016/j.molcel.2019.06.037
Okazaki KI*, Wöhlert D, Warnau J, Jung H, Yildiz O, Kühlbrandt W, Hummer G* (2019) Mechanism of the electroneutral sodium/proton antiporter PaNhaP from transition-path shooting. Nat Commun 10: 1742. http://dx.doi.org/10.1038/s41467-019-09739-0
Ortiz-Sánchez P, Villalba-Orero M, López-Olañeta MM, Larrasa-Alonso J, Sánchez-Cabo F, Martí-Gómez C, Camafeita E, Gómez-Salinero JM, Ramos-Hernández L, Nielsen PJ, Vázquez J, Müller-McNicoll M, García-Pavía P, Lara-Pezzi E (2019) Loss of SRSF3 in cardiomyocytes leads to decapping of contraction-related mRNAs and severe systolic dysfunction. Circ Res 125: 170-183. http://dx.doi.org/doi:10.1161/circresaha.118.314515
Porrati F, Barth S, Sachser R, Dobrovolskiy OV, Seybert A, Frangakis AS, Huth M (2019) Crystalline niobium carbide superconducting nanowires prepared by focused ion beam direct writing. ACS Nano: published online 2 May 2019. http://dx.doi.org/10.1021/acsnano.9b00059
Rangaraju V, Lauterbach M, Schuman EM (2019) Spatially stable mitochondrial compartments fuel local translation during plasticity. Cell: published online 3 January 2019. http://dx.doi.org/10.1016/j.cell.2018.12.013
Safarian S, Hahn A, Mills DJ, Radloff M, Eisinger ML, Nikolaev A, Meier-Credo J, Melin F, Miyoshi H, Gennis RB, Sakamoto J, Langer JD, Hellwig P, Kühlbrandt W*, Michel H* (2019) Active site rearrangement and structural divergence in prokaryotic respiratory oxidases. Science 366: 100-104. http://dx.doi.org/10.1126/science.aay0967
Sanchez de Groot N, Armaos A, Grana-Montes R, Alriquet M, Calloni G, Vabulas RM*, Tartaglia GG* (2019) RNA structure drives interaction with proteins. Nat Commun 10: 3246. http://dx.doi.org/10.1038/s41467-019-10923-5
Scherr J, Neuhaus A, Parey K, Klusch N, Murphy BJ, Zickermann V, Kühlbrandt W, Terfort A, Rhinow D (2019) Noncovalent functionalization of carbon substrates with hydrogels improves structural analysis of vitrified proteins by electron cryo-microscopy. ACS Nano: published online 22 May 2019. http://dx.doi.org/10.1021/acsnano.9b02651
Schnieders R, Wolter AC, Richter C, Wöhnert J, Schwalbe H*, Fürtig B* (2019) Novel (13) C-detected NMR experiments for the precise detection of RNA structure. Angew Chem Int Ed Engl: published online 27 May 2019. http://dx.doi.org/10.1002/anie.201904057
Shin D, Mukherjee R, Liu Y, Gonzalez A, Bonn F, Liu Y, Rogov VV, Heinz M, Stolz A, Hummer G, Dötsch V, Luo ZQ, Bhogaraju S, Dikic I (2019) Regulation of phosphoribosyl-linked serine ubiquitination by deubiquitinases DupA and DupB. Mol Cell: published online 12 November 2019. http://dx.doi.org/10.1016/j.molcel.2019.10.019
Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, de Silva K, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I (2019) Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition. EMBO J: e100938. http://dx.doi.org/10.15252/embj.2018100938
Slavov C, Yang C, Heindl AH, Wegner HA, Dreuw A, Wachtveitl J (2019) Thiophenylazobenzene - an alternative photoisomerization controlled by lone pairpi interaction. Angew Chem Int Ed Engl: published online 9 October 2019. http://dx.doi.org/10.1002/anie.201909739
Spahn C, Hurter F, Glaesmann M, Karathanasis C, Lampe M, Heilemann M (2019) Protein-specific, multi-color and 3D STED imaging in cells with DNA-labeled antibodies. Angew Chem Int Ed: published online 11 October 2019. http://dx.doi.org/10.1002/anie.201910115
Steuer Costa W, Van der Auwera P, Glock C, Liewald JF, Bach M, Schüler C, Wabnig S, Oranth A, Masurat F, Bringmann H, Schoofs L, Stelzer EHK, Fischer SC, Gottschalk A (2019) A GABAergic and peptidergic sleep neuron as a locomotion stop neuron with compartmentalized Ca2+ dynamics. Nat Commun 10: 4095. http://dx.doi.org/10.1038/s41467-019-12098-5
Timcenko M, Lyons JA, Januliene D, Ulstrup JJ, Dieudonné T, Montigny C, Ash MR, Karlsen JL, Boesen T, Kühlbrandt W, Lenoir G*, Moeller A*, Nissen P* (2019) Structure and autoregulation of a P4-ATPase lipid flippase. Nature: published online 26 June 2019. http://dx.doi.org/10.1038/s41586-019-1344-7
Vögele M, Bhaskara RM, Mulvihill E, van Pee K, Yildiz O, Kühlbrandt W, Müller DJ, Hummer G (2019) Membrane perforation by the pore-forming toxin pneumolysin. Proc Natl Acad Sci USA: published online 17 June 2019. http://dx.doi.org/10.1073/pnas.1904304116
von Bülow S, Siggel M, Linke M, Hummer G (2019) Dynamic cluster formation determines viscosity and diffusion in dense protein solutions. Proc Natl Acad Sci USA: published online 29 April 2019. http://dx.doi.org/10.1073/pnas.1817564116
Wu Q, Heidenreich D, Zhou S, Ackloo S, Krämer A, Nakka K, Lima-Fernandes E, Deblois G, Duan S, Vellanki RN, Li F, Vedadi M, Dilworth J, Lupien M, Brennan PE, Arrowsmith CH, Müller S, Fedorov O, Filippakopoulos P, Knapp S (2019) A chemical toolbox for the study of bromodomains and epigenetic signaling. Nat Commun 10: 1915. http://dx.doi.org/10.1038/s41467-019-09672-2
Yuki KE, Marei H, Fiskin E, Eva MM, Gopal AA, Schwartzentruber JA, Majewski J, Cellier M, Mandl JN, Vidal SM, Malo D*, Dikic I* (2019) CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection. Nat Microbiol: published online 8 July 2019. http://dx.doi.org/10.1038/s41564-019-0484-8
Zakrzewska S, Mehdipour AR, Malviya VN, Nonaka T, Koepke J, Muenke C, Hausner W, Hummer G, Safarian S, Michel H (2019) Inward-facing conformation of a multidrug resistance MATE family transporter. Proc Natl Acad Sci USA: published online 3 June 2019. http://dx.doi.org/10.1073/pnas.1904210116
2018
Ardèvol A, Hummer G (2018) Retinal isomerization and water-pore formation in channelrhodopsin-2. Proc Natl Acad Sci USA 115: 3557-3562. http://dx.doi.org/10.1073/pnas.1700091115
Barth K, Hank S, Spindler PE, Prisner TF, Tampé R, Joseph B (2018) Conformational coupling and trans-inhibition in the human antigen transporter ortholog TmrAB resolved with dipolar EPR spectroscopy. J Am Chem Soc 140: 4527-4533. http://dx.doi.org/10.1021/jacs.7b12409
Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schurmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I (2018) Cystathionine γ lyase sulfhydrates the RNA binding protein HuR to preserve endothelial cell function and delay atherogenesis. Circulation: published online 3 July 2018. http://dx.doi.org/10.1161/circulationaha.118.034757
Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P (2018) p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. Nat Commun 9: 1017. http://dx.doi.org/10.1038/s41467-018-03417-3
Braun S, Enculescu M, Setty ST, Cortes-Lopez M, de Almeida BP, Sutandy FXR, Schulz L, Busch A, Seiler M, Ebersberger S, Barbosa-Morais NL, Legewie S*, König J*, Zarnack K* (2018) Decoding a cancer-relevant splicing decision in the RON proto-oncogene using high-throughput mutagenesis. Nat Commun 9: 3315. http://dx.doi.org/10.1038/s41467-018-05748-7
Brown J, Behnam R, Coddington L, Tervo DGR, Martin K, Proskurin M, Kuleshova E, Park J, Phillips J, Bergs ACF, Gottschalk A, Dudman JT, Karpova AY (2018) Expanding the optogenetics toolkit by topological inversion of rhodopsins. Cell: published online 18 October 2018. http://dx.doi.org/10.1016/j.cell.2018.09.026
Cabrera-Orefice A, Yoga EG, Wirth C, Siegmund K, Zwicker K, Guerrero-Castillo S, Zickermann V, Hunte C, Brandt U (2018) Locking loop movement in the ubiquinone pocket of complex I disengages the proton pumps. Nat Commun 9: 4500. http://dx.doi.org/10.1038/s41467-018-06955-y
Chang C, Young LN, Morris KL, von Bulow S, Schoneberg J, Yamamoto-Imoto H, Oe Y, Yamamoto K, Nakamura S, Stjepanovic G, Hummer G, Yoshimori T, Hurley JH (2018) Bidirectional control of autophagy by BECN1 BARA domain dynamics. Mol Cell: published online 20 December 2018. http://dx.doi.org/10.1016/j.molcel.2018.10.035
Cremer S, Michalik KM, Fischer A, Pfisterer L, Jaé N, Winter C, Boon RA, Muhly-Reinholz M, John D, Uchida S, Weber C, Poller W, Günther S, Braun T, Li DY, Maegdefessel L, Matic Perisic L, Hedin U, Soehnlein O, Zeiher A, Dimmeler S (2018) Hematopoietic deficiency of the long non-coding RNA MALAT1 promotes atherosclerosis and plaque inflammation. Circulation: published online 28 November 2018. http://dx.doi.org/10.1161/circulationaha.117.029015
D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE (2018) An activity-based probe targeting non-catalytic, highly conserved amino acid residues within bromodomains. Angew Chem Int Ed: published online 27 December 2018. http://dx.doi.org/10.1002/anie.201807825
Davies KM, Blum TB, Kühlbrandt W (2018) Conserved in situ arrangement of complex I and III2 in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plants. P Natl Acad Sci USA 115: 3024-3029. http://dx.doi.org/10.1073/pnas.1720702115
Deussner-Helfmann NS, Auer A, Strauss MT, Malkusch S, Dietz MS, Barth HD, Jungmann R, Heilemann M (2018) Correlative single-molecule FRET and DNA-PAINT imaging. Nano Lett 18: 4626-4630. http://dx.doi.org/10.1021/acs.nanolett.8b02185
Diederichs T, Nguyen QH, Urban M, Tampé R*, Tornow M* (2018) Transparent nanopore cavity arrays enable highly parallelized optical studies of single membrane proteins on chip. Nano Lett 18: 3901-3910. http://dx.doi.org/10.1021/acs.nanolett.8b01252
Di Rita A, Peschiaroli A, P DA, Strobbe D, Hu Z, Gruber J, Nygaard M, Lambrughi M, Melino G, Papaleo E, Dengjel J, El Alaoui S, Campanella M, Dötsch V, Rogov VV, Strappazzon F, Cecconi F (2018) HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα. Nat Commun 9: 3755. http://dx.doi.org/10.1038/s41467-018-05722-3
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Segarra M, Aburto MR, Cop F, Llaó-Cid C, Härtl R, Damm M, Bethani I, Parrilla M, Husainie D, Schänzer A, Schlierbach H, Acker T, Mohr L, Torres-Masjoan L, Ritter M, Acker-Palmer A (2018) Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science 361, published online 24 August 2018. http://dx.doi.org/10.1126/science.aao2861
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