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Complementing conventional antibiotics

May 2018. Frankfurt scientists reveal atomic details for one of Legionella’s enzymatic weapons and develop first inhibitor

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Silicon chips with transparent microcavities for high-throughput optical studies of single membrane proteins

May 2018. Transparent chip design provides parallel and independent fluorescent readout of both cavities and buffer reservoir for unbiased single-transporter recordings

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Structure, mechanism, and regulation of the chloroplast ATP synthase

May 2018. High-resolution cryo-EM structure of an intact chloroplast ATP synthase provides new insights into an ancient biological process

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Stefan Knapp elected EMBO member

May 2018. Bridge between epigenetics and cancer treatment

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High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

May 2018. Optical cochlear implants restore auditory nerve activity in deaf mice

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Donated chemical probes for open science

April 2018. Innovative selective small molecule modulators of protein function now available as new tools for the scientific community

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Dynamics of untranslated regions of neuronal mRNA molecules

April 2018. Alternative 3′ UTRs modify the localization, regulatory potential, stability, and plasticity of mRNAs in neuronal compartments

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Robert Tampé receives ERC Advanced Investigator Grant

April 2018. EU supports research in Frankfurt on the immune response in cells with 2.5 million Euro

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Halogen‐aromatic pi-interactions modulate inhibitor residence time

April 2018. Strategy to prolong inhibitor residence times to increase efficacy of medical drugs

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Water emerges as key player in the opening of a membrane channel important in optogenetics

March 2018. Early functional dynamics of channelrhodopsin-2 explored through molecular simulations

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Opportunities for female scientists

March 2018. Science correspondent interviews Erin Schuman and other MPI directors

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AGameOfClones for genotyping of transgenic model organisms

March 2018. New universal vector concept for direct genotyping of transgenic organisms and systematic creation of homozygous lines

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Conserved arrangement of complex I and III2 in mitochondrial respiratory chain supercomplexes

March 2018. Mutual arrangement of the two largest components of the respiratory chain is essentially the same in mammals, plants and yeast, indicating that this arrangement is important for electron transfer

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Life times of metastable states guide regulatory signaling in transcriptional riboswitches

March 2018. Kinetic and simulation framework contributes to understanding of transcriptional riboswitches

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