News Archive
Probing the stoichiometry of membrane proteins by single-molecule localization microscopy |
December 2015. New counting strategy capable of reporting the oligomeric state of dense, membrane-bound protein complexes |
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Licht als filigranes Werkzeug |
CEF-Forscher nutzen Licht als Werkzeug, um zelluläre Prozesse aufzuklären - beleuchtet vom Wissenschaftsmagazin „Forschung Frankfurt“ |
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Role of CLPXP protease in energy metabolism |
December 2015. Identification of interactors and substrates suggest central role of the mitochondrial protease CLPXP in energy metabolism |
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Protein crystallography without crystals? |
December 2015. New project investigates a novel molecular sieve for structure determination of proteins |
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DFG funds autophagy research network |
November 2015. 11 million € for new collaborative research centre (SFB 1177) |
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New nanoscopic tools to study ligand-binding of receptors |
November 2015. Identifying and quantifying two ligand-binding sites while imaging membrane receptors |
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Achilleas Frangakis awarded ERC Proof of Concept grant |
October 2015. Funding for tomographic reconstruction algorithm Super-Sampling SART |
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Patent granted for new DNP equipment |
October 2015. Ten to hundred-fold higher sensitivity achieved |
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Membership of Academia Europaea |
October 2015. Academia Europaea elects Ivan Dikic as new member |
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Ivan Dikic appointed senior editor of eLife |
October 2015. Senior editorship of non-profit research journal supported by the Howard Hughes Medical Institute, Max Planck Society and Wellcome Trust |
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Model system for the study of heartbeat irregularities |
September 2015. Optogenetically paced muscular pump of C. elegans as model system for cardiac arrythmias |
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Start of EU network iNEXT |
September 2015. Access to state-of-the-art infrastructures for structural biology for scientists across Europe |
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Novel optogenetic tool |
September 2015. Novel optogenetic tool for light-dependent generation of the cellular signaling molecule cGMP |
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Call for applications: GIERSCH Endowed Professorship (W2) for Bioinformatics |
2 September 2015. A generous initiative of the Karin and Carlo Giersch Foundation enables the Faculty of Biosciences of the Johann Wolfgang Goethe-University Frankfurt am Main in cooperation with the Frankfurt Institute for... |
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New set of standards allows accurate protein counting |
August 2015. A selection of easy to use bacterial homo-oligomers for the validation of molecular counting methods using fluorescence microscopy |
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SLAP: Small labeling pair for single-molecule super-resolution imaging |
August 2015. New method avoids masking by large probes yet achieves labeling specificity comparable to antibodies |
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Formation of ordered nanoclusters controls cell-cell contact fluidity |
July 2015. Visualizing single cadherins within cell membranes at nanometric resolution showed that they arrange in ordered clusters. Disruption of the cis-interface indicates that formation of oligomeric clusters controls the... |
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Harald Schwalbe receives award for "Best Doctoral Supervision" |
July 2015. The central graduate academy of Goethe University Frankfurt awards prize to recognize outstanding performance as PhD supervisor |
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When quality control fails |
June 2015. New autophagy receptor with central role in cellular quality control discovered |
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Frankfurter Forscherin an Schaltstelle der deutschen Hochschulentwicklung |
Mai 2015. Simone Fulda übernimmt die Leitung des Ausschusses für Forschungsbauten im Wissenschaftsrat |
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DFG extends SFB 902 funding |
May 2015. Collaborative research centre "Molecular Principles of RNA-based Regulation" receives 8.9 million Euro of research funding. |
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EMBO announces new members for 2015 |
May 2015. Amparo Acker-Palmer elected EMBO Member |
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Novel gene causing amyotrophic lateral sclerosis |
May 2015. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia |
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From heart attacks to cancer: Which role do long, non-coding RNAs play? |
May 2015. Biologist Stefanie Dimmeler receives ERC Advanced Grant |
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How do neurons and blood vessels “talk” to each other? |
May 2015. Neurobiologist Amparo Acker-Palmer receives ERC Advanced Grant |
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Enrico Schleiff re-elected Vice President of Goethe University |
April 2015. Enrico Schleiff starts his new three-year term in May 2015 |
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Zooming into wound healing |
April 2015. Analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography |
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Next generation optogenetics: tool development and application |
März 2015. DFG funds new priority programme with 6 million euros |
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Telling new from old – visualization of newly made proteins in a cell |
March 2015. New strategy to visualize within cells specific recently synthesized proteins with both spatial and temporal resolution |
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How ATP production is coupled to proton translocation |
February 2015. Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase |
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Circular RNA in the brain |
February 2015. CircRNAs show high abundance in brain tissue and brain-expressed circRNAs are made from host genes that code for synaptic proteins |
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Ultrasensitive quantification of TAP-dependent antigen compartmentalization |
February 2015. New flow cytometry assay allows monitoring of transporter activity under close to physiological conditions in scarce primary immune cells |
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Spatiotemporal control of puromycin application with UV illumination |
February 2015. New tool for the study of locatised protein synthesis |
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Annular lipids linked to flippase activity of a transporter |
February 2015. Lipids important for structure and function of an ABC transporter revealed |
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PLEKHM1: A multifunctional adaptor for the endolysosomal system |
January 2015. The protein PLEKHM1 regulates autophagosome-lysosome fusion as well as Salmonella-containing vacuole biogenesis and infection. |
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Light sheet-based fluorescence microscopy is the Nature Method of the Year 2014 |
January 2015. International recognition for the major contribution of the microscopy technology developed by Ernst Stelzer and his group. |
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Mechanistic insight from crystal structure of mitochondrial complex I |
January 2015. 3D structure of complex I at 3.6 to 3.9 Å resolution published in the journal Science. |
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