english deutsch 

News Archive

Development of a synthetic TAP inhibitor that can be cleaved by light

December 2018. Light-controlled TAP inhibitor expands the repertoire of chemical intervention tools for the study of immunological processes

[more]

High quality photoswitchable regulatory RNA tool developed

December 2018. New riboswitch aptamer with selective and isomer-specific binding to a novel photoswitchable ligand suitable for biological applications

[more]

New insights into the dynamics of riboswitch activation

December 2018. Structure-guided fluorescence labelling reveals a two-step binding mechanism of neomycin to its RNA aptamer

[more]

DFG approves CRC 1361 on DNA repair and genome stability

December 2018. Scientists from Johannes Gutenberg University, IMB, TU Darmstadt, LMU and Goethe University have joined forces to establish a new research hub in this biomedically highly relevant field

[more]

Four CEF members are among the most highly cited researchers worldwide

November 2018. Ivan Dikic, Stefanie Dimmeler, Stefan Knapp and Ernst Stelzer belong to the top 1% scientists cited

[more]

DFG extends funding for CLiC

November 2018. The research training group "Complex Scenarios of Light-Control" has successfully applied for a second funding period

[more]

New insights into the catalytic mechanism of an ABC membrane transporter

November 2018. Advanced spectroscopic approaches reveal unexplored nucleotide binding modes for the ABC exporter MsbA

[more]

Erin Schuman has been awarded the Mika Salpeter Lifetime Achievement Award

November 2018. The Society for Neuroscience recognizes Erin Schuman for her outstanding achievements in neuroscience and for promoting the professional advancement of women

[more]

Regulation of food-related behaviour by dopamine and neuropeptides may have been conserved during evolution

November 2018. Food sensation modulates locomotion by dopamine and neuropeptide signaling in a distributed neuronal network

[more]

Understanding quality control in the cellular immune system

October 2018. The biochemist Robert Tampé will receive € 1.5 million for a Koselleck project with the German Research Foundation starting in 2019

[more]

Expanding the optogenetics toolkit

October 2018. Topological inversion of rhodopsins yields new variants with unique properties

[more]

Live-cell labeling of endogenous proteins with high precision by transduced nanobodies

October 2018. High-throughput strategy to simultaneously target multiple endogenous proteins in living cells with nanometer resolution

[more]

Ivan Dikic appointed as Max Planck Fellow

October 2018. The Max Planck Institute of Biophysics has announced that Ivan Dikic has been appointed a Fellow of the Max Planck Society for a 5-year-term. This includes supervision of a small working group at the Frankfurt-based...

[more]

Cardiovascular Researchers in Frankfurt and Giessen are delighted about their success in the Excellence Strategy

September 2018. Joint project between Justus-Liebig-University, Goethe University and Max-Planck-Institute clears the last hurdle

[more]

Forschen an neuen Therapieformen zur Behandlung von Tumorerkrankungen

September 2018. Minister stellt das Frankfurt Cancer Institute vor, das am Campus Niederrad entstehen wird

[more]

A new piece in the puzzle of neuronal locomotion control

September 2018. Functionally asymmetric motor neurons contribute to the coordination of C. elegans movement

[more]

Self-healing dye for single-molecule fluorescence imaging

September 2018. TrisNTA fluorophores allow specific labeling and increased photostability

[more]

Decoding a cancer-relevant splicing decision

September 2018. High-throughput mutagenesis approach decodes a cancer-relevant splicing decision in the RON proto-oncogene

[more]

Conformational switch in the ribosomal protein S1 guides unfolding of structured RNAs for translation initiation

September 2018. Understanding the intricate coupling of protein and RNA folding dynamics that enable translation initiation of structured mRNAs

[more]

Blood vessels instruct brain development

August 2018. Neurovascular communication in the brain

[more]

New synthesis approach allows modification of long RNAs in a position-specific manner for biophysical studies

July 2018. Method enables incorporation of a wide range of modifications at any desired position in RNAs of any lengths

[more]

Correlative single-molecule FRET and DNA-PAINT imaging

July 2018. Correlative single-molecule FRET and DNA-PAINT imaging opens the door for accurate distance readout in the 1–10 nm range

[more]

68th Lindau Nobel Laureate Meeting

July 2018. Hartmut Michel’s presentation to an international audience of young scientists is available online

[more]

Complexities of organelle biology

July 2018. With the complexities of organelle communication and their dynamics under intense investigation, what are the new principles that are emerging, and where is the field headed?

[more]

Dynamics of nucleic acids at room temperature revealed by pulsed EPR

June 2018. New method to study dynamics of biomolecules with atomistic resolution at physiological temperature

[more]

Optimizing nanotool structure for tracking proteins

June 2018. Scaffold design of trivalent chelator heads dictates high-affinity and stable His-tagged protein labeling in vitro and in cellulo

[more]

Complementing conventional antibiotics

May 2018. Frankfurt scientists reveal atomic details for one of Legionella’s enzymatic weapons and develop first inhibitor

[more]

Silicon chips with transparent microcavities for high-throughput optical studies of single membrane proteins

May 2018. Transparent chip design provides parallel and independent fluorescent readout of both cavities and buffer reservoir for unbiased single-transporter recordings

[more]

Structure, mechanism, and regulation of the chloroplast ATP synthase

May 2018. High-resolution cryo-EM structure of an intact chloroplast ATP synthase provides new insights into an ancient biological process

[more]

Stefan Knapp elected EMBO member

May 2018. Bridge between epigenetics and cancer treatment

[more]

High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

May 2018. Optical cochlear implants restore auditory nerve activity in deaf mice

[more]

Donated chemical probes for open science

April 2018. Innovative selective small molecule modulators of protein function now available as new tools for the scientific community

[more]

Dynamics of untranslated regions of neuronal mRNA molecules

April 2018. Alternative 3′ UTRs modify the localization, regulatory potential, stability, and plasticity of mRNAs in neuronal compartments

[more]

Scholarships available for international Goethe University Master students

April 2018. Full scholarships available for excellent applicants from all over the world with a first degree from a non-German university

[more]

Robert Tampé receives ERC Advanced Investigator Grant

April 2018. EU supports research in Frankfurt on the immune response in cells with 2.5 million Euro

[more]

Halogen‐aromatic pi-interactions modulate inhibitor residence time

April 2018. Strategy to prolong inhibitor residence times to increase efficacy of medical drugs

[more]

Water emerges as key player in the opening of a membrane channel important in optogenetics

March 2018. Early functional dynamics of channelrhodopsin-2 explored through molecular simulations

[more]

Opportunities for female scientists

March 2018. Science correspondent interviews Erin Schuman and other MPI directors

[more]

AGameOfClones for genotyping of transgenic model organisms

March 2018. New universal vector concept for direct genotyping of transgenic organisms and systematic creation of homozygous lines

[more]

Conserved arrangement of complex I and III2 in mitochondrial respiratory chain supercomplexes

March 2018. Mutual arrangement of the two largest components of the respiratory chain is essentially the same in mammals, plants and yeast, indicating that this arrangement is important for electron transfer

[more]

Life times of metastable states guide regulatory signaling in transcriptional riboswitches

March 2018. Kinetic and simulation framework contributes to understanding of transcriptional riboswitches

[more]

Super-chelators for advanced protein labeling in living cells

February 2018. New chelators permit kinetic profiling, multiplexed labeling of His6 and His12-tagged proteins as well as single-molecule based super-resolution imaging

[more]

New target for fertility protective therapy

February 2018. Activation of p63 in oocytes requires consecutive interplay of CHK2 and CK1 kinases

[more]

New proteins for new memories

February 2018. Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses

[more]

Simone Fulda elected vice-president of Goethe University Frankfurt

February 2018. Childhood cancer expert Simone Fulda elected by the senate of Goethe University as vice-president for research and academic infrastructure.

[more]

Clonal expansion of endothelial cells contributes to blood vessel growth

January 2018. Mature endothelial cells have the capacity to clonally expand and contribute to ischemia-induced newly formed vessels

[more]

Cause of severe hereditary disease revealed

January 2018. Protein aggregation of the p63 transcription factor cause the severe skin fragility in AEC syndrome

[more]

Regulation of endothelial gene expression by a long non-coding RNA

January 2018. The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

[more]

Stefan Knapp is among the most cited protein scientists in Europe

January 2018. Lab Times ranking lists Stefan Knapp as the 10th most cited European protein scientist

[more]

Subtype specificity in human peptide GPCRs by DNP-enhanced solid-state NMR

January 2018. Study solves puzzle how closely related receptors with high sequence similarity differentiate between very similar peptides

[more]

Archive:

2019

2018

2017

2016

2015

2014

2013

2012

2011

2010

2009

2008

2007