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News Archive

Probing the stoichiometry of membrane proteins by single-molecule localization microscopy

December 2015. New counting strategy capable of reporting the oligomeric state of dense, membrane-bound protein complexes


Licht als filigranes Werkzeug

CEF-Forscher nutzen Licht als Werkzeug, um zelluläre Prozesse aufzuklären - beleuchtet vom Wissenschaftsmagazin „Forschung Frankfurt“


Role of CLPXP protease in energy metabolism

December 2015. Identification of interactors and substrates suggest central role of the mitochondrial protease CLPXP in energy metabolism


Protein crystallography without crystals?

December 2015. New project investigates a novel molecular sieve for structure determination of proteins


DFG funds autophagy research network

November 2015. 11 million € for new collaborative research centre (SFB 1177)


New nanoscopic tools to study ligand-binding of receptors

November 2015. Identifying and quantifying two ligand-binding sites while imaging membrane receptors


Achilleas Frangakis awarded ERC Proof of Concept grant

October 2015. Funding for tomographic reconstruction algorithm Super-Sampling SART


Patent granted for new DNP equipment

October 2015. Ten to hundred-fold higher sensitivity achieved


Membership of Academia Europaea

October 2015. Academia Europaea elects Ivan Dikic as new member


Ivan Dikic appointed senior editor of eLife

October 2015. Senior editorship of non-profit research journal supported by the Howard Hughes Medical Institute, Max Planck Society and Wellcome Trust


Model system for the study of heartbeat irregularities

September 2015. Optogenetically paced muscular pump of C. elegans as model system for cardiac arrythmias


Start of EU network iNEXT

September 2015. Access to state-of-the-art infrastructures for structural biology for scientists across Europe


Novel optogenetic tool

September 2015. Novel optogenetic tool for light-dependent generation of the cellular signaling molecule cGMP


Call for applications: GIERSCH Endowed Professorship (W2) for Bioinformatics

2 September 2015. A generous initiative of the Karin and Carlo Giersch Foundation enables the Faculty of Biosciences of the Johann Wolfgang Goethe-University Frankfurt am Main in cooperation with the Frankfurt Institute for...


New set of standards allows accurate protein counting

August 2015. A selection of easy to use bacterial homo-oligomers for the validation of molecular counting methods using fluorescence microscopy


SLAP: Small labeling pair for single-molecule super-resolution imaging

August 2015. New method avoids masking by large probes yet achieves labeling specificity comparable to antibodies


Formation of ordered nanoclusters controls cell-cell contact fluidity

July 2015. Visualizing single cadherins within cell membranes at nanometric resolution showed that they arrange in ordered clusters. Disruption of the cis-interface indicates that formation of oligomeric clusters controls the...


Harald Schwalbe receives award for "Best Doctoral Supervision"

July 2015. The central graduate academy of Goethe University Frankfurt awards prize to recognize outstanding performance as PhD supervisor


When quality control fails

June 2015. New autophagy receptor with central role in cellular quality control discovered


Frankfurter Forscherin an Schaltstelle der deutschen Hochschulentwicklung

Mai 2015. Simone Fulda übernimmt die Leitung des Ausschusses für Forschungsbauten im Wissenschaftsrat


DFG extends SFB 902 funding

May 2015. Collaborative research centre "Molecular Principles of RNA-based Regulation" receives 8.9 million Euro of research funding.


EMBO announces new members for 2015

May 2015. Amparo Acker-Palmer elected EMBO Member


Novel gene causing amyotrophic lateral sclerosis

May 2015. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia


From heart attacks to cancer: Which role do long, non-coding RNAs play?

May 2015. Biologist Stefanie Dimmeler receives ERC Advanced Grant


How do neurons and blood vessels “talk” to each other?

May 2015. Neurobiologist Amparo Acker-Palmer receives ERC Advanced Grant


Enrico Schleiff re-elected Vice President of Goethe University

April 2015. Enrico Schleiff starts his new three-year term in May 2015


Zooming into wound healing

April 2015. Analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography


Next generation optogenetics: tool development and application

März 2015. DFG funds new priority programme with 6 million euros


Telling new from old – visualization of newly made proteins in a cell

March 2015. New strategy to visualize within cells specific recently synthesized proteins with both spatial and temporal resolution


How ATP production is coupled to proton translocation

February 2015. Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase


Circular RNA in the brain

February 2015. CircRNAs show high abundance in brain tissue and brain-expressed circRNAs are made from host genes that code for synaptic proteins


Ultrasensitive quantification of TAP-dependent antigen compartmentalization

February 2015. New flow cytometry assay allows monitoring of transporter activity under close to physiological conditions in scarce primary immune cells


Spatiotemporal control of puromycin application with UV illumination

February 2015. New tool for the study of locatised protein synthesis


Annular lipids linked to flippase activity of a transporter

February 2015. Lipids important for structure and function of an ABC transporter revealed


PLEKHM1: A multifunctional adaptor for the endolysosomal system

January 2015. The protein PLEKHM1 regulates autophagosome-lysosome fusion as well as Salmonella-containing vacuole biogenesis and infection.


Light sheet-based fluorescence microscopy is the Nature Method of the Year 2014

January 2015. International recognition for the major contribution of the microscopy technology developed by Ernst Stelzer and his group.


Mechanistic insight from crystal structure of mitochondrial complex I

January 2015. 3D structure of complex I at 3.6 to 3.9 Å resolution published in the journal Science.