December 2016. Coupled ATPase-adenylate kinase activity in ABC transporters

December 2016. New photo-tether strategy provides robust and versatile tool for the light-activation of longer functional oligonucleotides

December 2016. Essay highlights milestones that lead to the discovery of the molecular principles governing autophagy

December 2016. LOEWE programme Ubiquitin Networks extended

December 2016. Phosphoribosylation of ubiquitin promotes serine ubiquitination and impairs conventional ubiquitination

December 2016. International marketing concept of UBAUT networks receives DFG award

November 2016. €12 million for research in the Rhine-Main area on molecular and cellular mechanisms of neural homeostasis

November 2016. Structure with and without nucleic acids solved at 3.8 Å resolution by cryo-electron microscopy

November 2016. Structure of ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry

October 2016. Researchers discover a “sugar-code” for neuronal membrane proteins

October 2016. Newly synthetized enzymes must fold correctly and associate with cofactors to reach their functional state. Frankfurt scientists led by Martin Vabulas have now demonstrated that cofactor deprivation due to vitamin...

October 2016. Pre-initiation and initiation conformations of virus promoter RNA probed by single-molecule FRET

October 2016. Three-dimensional control of DNA hybridization by orthogonal two-color two-photon uncaging

September 2016. Bacterial invasion impacts several critical pathways of the host cell

September 2016. The human transporter associated with antigen processing (TAP) selects peptides for export into the endoplasmic reticulum and subsequent loading onto major histocompatibility complex class I molecules to trigger...

September 2016. EB1 interacts with outwardly curved and straight regions of the microtubule lattice

September 2016. Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation

August 2016. Previously unknown subunit architecture of the dimer interface in the membrane revealed

July 2016. Can the unique synthetic principle of megasynthases be employed for the production of antibiotics and other drugs via biomimetic approaches?

June 2016. Cylinder-shaped structures measure saturated and unsaturated fatty acids

June 2016. The CUE domain of Cue1 aligns growing ubiquitin chains with ubiquitin-conjugating enzyme 7 for rapid elongation

April 2016. The structure and arrangement of the heme cofactors of bd oxidase bear little resemblance to those of other membrane-spanning oxidases

April 2016. Mechanism revealed how p63 is kept inactive yet rapidly eliminates oocytes in response to a few DNA double strand breaks

March 2016. New open source software establishes streamlined approach for designing and validating super-resolution microscopy experiments

February 2016. Endocrine cells derived from human pancreas organoids for cell-based therapy of type 1 diabetes

February 2016. NMR reveals multiple conformational and oxidation states of synonymous codon variants

January 2016. Rules and self-organizing properties of post-embryonic plant organ cell division patterns

Efficient and minimally disruptive light-triggered tracing of native proteins and subsequent super-resolution imaging of live-cell phenomena.

January 2016. Award recognizes outstanding contribution in technology innovation in the life sciences

January 2016. Autophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation in C. elegans

January 2016. The central scaffold protein PCNA appears in replicating mammalian cells as two populations of slow and fast diffusion

January 2016. New project aims at rewiring living cells by in situ-lateral organization of membrane receptors

January 2016. High-affinity trans-splicing directed by a minimal interaction pair