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News Archive

Probing the stoichiometry of membrane proteins by single-molecule localization microscopy

December 2015. New counting strategy capable of reporting the oligomeric state of dense, membrane-bound protein complexes

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Licht als filigranes Werkzeug

CEF-Forscher nutzen Licht als Werkzeug, um zelluläre Prozesse aufzuklären - beleuchtet vom Wissenschaftsmagazin „Forschung Frankfurt“

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Role of CLPXP protease in energy metabolism

December 2015. Identification of interactors and substrates suggest central role of the mitochondrial protease CLPXP in energy metabolism

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Protein crystallography without crystals?

December 2015. New project investigates a novel molecular sieve for structure determination of proteins

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DFG funds autophagy research network

November 2015. 11 million € for new collaborative research centre (SFB 1177)

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New nanoscopic tools to study ligand-binding of receptors

November 2015. Identifying and quantifying two ligand-binding sites while imaging membrane receptors

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Achilleas Frangakis awarded ERC Proof of Concept grant

October 2015. Funding for tomographic reconstruction algorithm Super-Sampling SART

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Patent granted for new DNP equipment

October 2015. Ten to hundred-fold higher sensitivity achieved

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Membership of Academia Europaea

October 2015. Academia Europaea elects Ivan Dikic as new member

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Ivan Dikic appointed senior editor of eLife

October 2015. Senior editorship of non-profit research journal supported by the Howard Hughes Medical Institute, Max Planck Society and Wellcome Trust

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Model system for the study of heartbeat irregularities

September 2015. Optogenetically paced muscular pump of C. elegans as model system for cardiac arrythmias

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Start of EU network iNEXT

September 2015. Access to state-of-the-art infrastructures for structural biology for scientists across Europe

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Novel optogenetic tool

September 2015. Novel optogenetic tool for light-dependent generation of the cellular signaling molecule cGMP

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Call for applications: GIERSCH Endowed Professorship (W2) for Bioinformatics

2 September 2015. A generous initiative of the Karin and Carlo Giersch Foundation enables the Faculty of Biosciences of the Johann Wolfgang Goethe-University Frankfurt am Main in cooperation with the Frankfurt Institute for...

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New set of standards allows accurate protein counting

August 2015. A selection of easy to use bacterial homo-oligomers for the validation of molecular counting methods using fluorescence microscopy

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SLAP: Small labeling pair for single-molecule super-resolution imaging

August 2015. New method avoids masking by large probes yet achieves labeling specificity comparable to antibodies

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Formation of ordered nanoclusters controls cell-cell contact fluidity

July 2015. Visualizing single cadherins within cell membranes at nanometric resolution showed that they arrange in ordered clusters. Disruption of the cis-interface indicates that formation of oligomeric clusters controls the...

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Harald Schwalbe receives award for "Best Doctoral Supervision"

July 2015. The central graduate academy of Goethe University Frankfurt awards prize to recognize outstanding performance as PhD supervisor

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When quality control fails

June 2015. New autophagy receptor with central role in cellular quality control discovered

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Frankfurter Forscherin an Schaltstelle der deutschen Hochschulentwicklung

Mai 2015. Simone Fulda übernimmt die Leitung des Ausschusses für Forschungsbauten im Wissenschaftsrat

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DFG extends SFB 902 funding

May 2015. Collaborative research centre "Molecular Principles of RNA-based Regulation" receives 8.9 million Euro of research funding.

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EMBO announces new members for 2015

May 2015. Amparo Acker-Palmer elected EMBO Member

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Novel gene causing amyotrophic lateral sclerosis

May 2015. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

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From heart attacks to cancer: Which role do long, non-coding RNAs play?

May 2015. Biologist Stefanie Dimmeler receives ERC Advanced Grant

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How do neurons and blood vessels “talk” to each other?

May 2015. Neurobiologist Amparo Acker-Palmer receives ERC Advanced Grant

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Enrico Schleiff re-elected Vice President of Goethe University

April 2015. Enrico Schleiff starts his new three-year term in May 2015

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Zooming into wound healing

April 2015. Analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography

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Next generation optogenetics: tool development and application

März 2015. DFG funds new priority programme with 6 million euros

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Telling new from old – visualization of newly made proteins in a cell

March 2015. New strategy to visualize within cells specific recently synthesized proteins with both spatial and temporal resolution

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How ATP production is coupled to proton translocation

February 2015. Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase

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Circular RNA in the brain

February 2015. CircRNAs show high abundance in brain tissue and brain-expressed circRNAs are made from host genes that code for synaptic proteins

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Ultrasensitive quantification of TAP-dependent antigen compartmentalization

February 2015. New flow cytometry assay allows monitoring of transporter activity under close to physiological conditions in scarce primary immune cells

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Spatiotemporal control of puromycin application with UV illumination

February 2015. New tool for the study of locatised protein synthesis

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Annular lipids linked to flippase activity of a transporter

February 2015. Lipids important for structure and function of an ABC transporter revealed

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PLEKHM1: A multifunctional adaptor for the endolysosomal system

January 2015. The protein PLEKHM1 regulates autophagosome-lysosome fusion as well as Salmonella-containing vacuole biogenesis and infection.

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Light sheet-based fluorescence microscopy is the Nature Method of the Year 2014

January 2015. International recognition for the major contribution of the microscopy technology developed by Ernst Stelzer and his group.

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Mechanistic insight from crystal structure of mitochondrial complex I

January 2015. 3D structure of complex I at 3.6 to 3.9 Å resolution published in the journal Science.

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