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News Archive

High resolution structure of a bacterial terminal oxidase provides clues for antimicrobial drug development

October 2019. Publication in Science reports active site rearrangement and structural divergence in prokaryotic respiratory oxidases


Congratulations to Ernst Bamberg

September 2019. Ernst Bamberg named a Citation Laureate


The sleep neuron in threadworms is also a stop neuron

September 2019. Sleep or stop? The RIS neuron has both functions


Surprising insight into Legionnaires' disease

July 2019. Frankfurt researchers have explained the mechanism of regulator SidJ in detail


Location matters: The production site predicts protein abundance

July 2019. How mRNA localization and protein synthesis sites influence dendritic protein distribution and dynamics


Translocation cycle of asymmetric ABC exporters resolved

July 2019. High resolution Cryo-EM structures delineate the full cycle of conformational changes of asymmetric ABC exporter proteins


New insights into the remodelling of mitochondria

July 2019. Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1


A tug of war: how Salmonella tackles cellular defense mechanisms

July 2019. CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection


Simone Fulda elected member of Leopoldina

July 2019. Cancer researcher from Frankfurt elected to Germany's National Academy of Sciences


New insights into ribosome recycling with the enzyme ABCE1

July 2019. The twin-ATPase ABCE1 controls ribosome recycling by an asymmetric dynamic conformational equilibrium


Proteins are needed for memory, but where and when?

July 2019. New research method enables scientists to switch protein synthesis in individual nerve cells on and off at will


Understanding and modulating partial FXR activation

July 2019. The nuclear receptor protein FXR is a promising drug target for the treatment of liver diseases and diabetes


Structure and autoregulation of a flippase that drives active transport of phospholipids

July 2019. Cryo EM study captures the progressive steps from the inhibited flippase to the fully activated conformation


EM study resolves a key question about the functioning of ATP synthase

June 2019. Separation of independent rotary states of mitochondrial ATP synthase reveals the basis of the flexible F1-Fo coupling


High school students visit BMLS

June 2019. Every year CEF and BMLS introduce high school students to real life science research


Neuer LOEWE-Schwerpunkt über Mehrskalen-Modellierung in den Lebenswissenschaften

Juni 2019. Hessisches Ministerium für Wissenschaft und Kunst fördert neue Frankfurter LOEWE-Schwerpunkte


BMLS scientist wins PhD award

June 2019. Frederic Strobl receives award for his comparative study of the embryonic morphogenesis of several insect species


Inward-facing conformation of a multidrug resistance MATE family transporter

June 2019. The use of native lipids allowed visualization of a MATE transporter in the long-sought-after inward-facing conformation


Drei SGC Meetings in Frankfurt

Juni 2019. Frankfurter SGC Veranstaltungen bringen hochrangige Vertreter von Wissenschaft, Wohltätigkeitsorganisationen und Pharmafirmen zusammen


BMLS Josef Buchman Awards Ceremony 2019

June 2019. BMLS celebrates the achievements of its young scientists with the presentation of the BMLS Josef Buchman Awards


Robert Tampé elected EMBO member

June 2019. Specialist in immune research has been elected a member of the European Molecular Biology Organization


A chemical toolbox for the study of epigenetic signaling

May 2019. Chemical probe-set to aid the discovery of new physiological roles of bromodomain proteins in health and and disease


Successful CRC proposals

May 2019. DFG extends funding for the RNA CRC 902 and approves new CRCs in the area of RNA and cancer research


Protein supply in long nerves: how do neurons do it?

May 2019. High proportions of axon terminals contain protein synthesis machinery


Scholarships available for international Master students at Goethe University

May 2019. Full scholarships available for excellent applicants from all over the world


Functional cooperativity of dimers of an important solute carrier family

May 2019. Combined structural and functional data define the framework for a mechanistic understanding of functional cooperativity in SLC26 dimers.


Transport mechanism of an electroneutral antiporter solved

April 2019. Transport cycle of PaNhaP, a functional homologue of an important human drug target, solved by transition-path shooting


Ivan Dikic elected to the American Academy of Arts and Sciences

April 2019. IBC2 director is honoured for his work in deciphering the role of ubiquitination and autophagy as quality control pathways in cells


Study suggests paradigm shift about the way microbial rhodopsins function

April 2019. Light-dependent functionally relevant cross talk between individual rhodopsins of a microbial rhodopsin oligomer


Ernst Bamberg receives Rumford Prize of the American Academy of Arts and Sciences

April 2019. Recognition for contribution to the discovery and development of optogenetics


New EU project at BMLS

April 2019. EU project BRIGHTER: bio-printing 3D tissues with light sheets


CRISPR/Cas libraries open new avenues in cancer research

March 2019. Innovative methods lead to foundation of start-up Vivlion GmbH


Humboldt research fellow investigates rare hereditary disease

March 2019. Rukmini Mukherjee investigates what role reticulon mutations play in hereditary spastic paraplegia


Dimers of ATP synthase self-assemble into rows and induce membrane curvature

February 2019. Mitochondrial ATP synthase dimers assemble spontaneously into rows upon membrane reconstitution and these rows bend the membrane


Protective role of an lncRNA against atherosclerosis

January 2019. Deficiency of the long non-coding RNA MALAT1 promotes atherosclerosis and plaque inflammation


BoTox toxin turned into a precision research tool

January 2019. Photoactivatable botulinum toxin for inducible control of neurotransmission


Plant-specific ribosome biogenesis factors

January 2019. Discovery of plant-specific ribosome biogenesis factors with essential function in rRNA processing


What fuels memory?

January 2019. Mitochondria are essential for local protein synthesis and synaptic plasticity in neurons