News Archive

New findings published on the human protein complex Hsp90-Cdc37

Molecular mechanism of inhibition of human protein complex Hsp90-Cdc37, a kinome chaperone-cochaperone, by triterpene celastrol
Sridhar Sreeramulu, Santosh Lakshmi Gande, Michael Göbel, Harald Schwalbe (2009) Angew. Chem. Int. Ed. (in press) More ...

 

also recently published:

The human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopy.
Sreeramulu S, Jonker HR, Langer T, Richter C, Lancaster CR, Schwalbe H. (2009) J Biol Chem. 2009 Feb 6;284(6):3885-96. Epub 2008 Dec 10. More ...

Human Cdc37-Hsp90 docking model based on NMR