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Alexander Gottschalk publishes paper on optogenetic analysis of synaptic function in Nature Methods

New method for time-resolved and quantitative assessment of synaptic function: A team of scientists headed by Adjunct Investigator Alexander Gottschalk developed a new method called optogenetic investigation of neurotransmission (OptIoN) for time-resolved and quantitative assessment of synaptic function via behavioral and electrophysiological analyses. This method involves photo-triggering release of acetylcholine or γ-aminobutyric acid at Caenorhabditis elegans neuromuscular junctions using targeted expression of Chlamydomonas reinhardtii Channelrhodopsin-2. This work was recently published in Nature Methods.

Liewald JF, Brauner M, Stephens GJ, Bouhours M, Schultheis C, Zhen M, Gottschalk A (2008) Optogenetic analysis of synaptic function. Nature Methods. online publication 14 September 2008. DOI:10.1038/NMETH.1252

[Abstract]
[Article(pdf)]
[Further Information about Alexander Gottschalk's research]